Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine

M Brown, J Li, C Moraes, M Tabrizian, NYK Li-Jessen - Biomaterials, 2022 - Elsevier
Extracellular matrix is rich in biomolecules including structural proteins,
glycosaminoglycans, and small molecules that are important for the maintenance and repair …

Extracellular matrix hydrogels from decellularized tissues: Structure and function

LT Saldin, MC Cramer, SS Velankar, LJ White… - Acta biomaterialia, 2017 - Elsevier
Extracellular matrix (ECM) bioscaffolds prepared from decellularized tissues have been
used to facilitate constructive and functional tissue remodeling in a variety of clinical …

Extracellular‐matrix‐reinforced bioinks for 3D bioprinting human tissue

MM De Santis, HN Alsafadi, S Tas… - Advanced …, 2021 - Wiley Online Library
Recent advances in 3D bioprinting allow for generating intricate structures with dimensions
relevant for human tissue, but suitable bioinks for producing translationally relevant tissue …

Extracellular matrix hydrogel therapies: In vivo applications and development

MT Spang, KL Christman - Acta biomaterialia, 2018 - Elsevier
Decellularized extracellular matrix (ECM) has been widely used for tissue engineering
applications and is becoming increasingly versatile as it can take many forms, including …

Designing decellularized extracellular matrix‐based bioinks for 3D bioprinting

A Abaci, M Guvendiren - Advanced healthcare materials, 2020 - Wiley Online Library
Abstract 3D bioprinting is an emerging technology to fabricate tissues and organs by
precisely positioning cells into 3D structures using printable cell‐laden formulations known …

Organ-derived decellularized extracellular matrix: a game changer for bioink manufacturing?

D Choudhury, HW Tun, T Wang, MW Naing - Trends in biotechnology, 2018 - cell.com
The extracellular matrix (ECM) comprises a complex milieu of proteins and other growth
factors that provide mechanical, biophysical, and biochemical cues to cells. The ECM is …

Decellularization systems and devices: State-of-the-art

D Choudhury, M Yee, ZLJ Sheng, A Amirul, MW Naing - Acta biomaterialia, 2020 - Elsevier
Extracellular matrix (ECM) is a natural biomaterial scaffold that provides biochemical and
structural support to its surrounding cells, forming tissue and respective organs. These ECM …

Human lung extracellular matrix hydrogels resemble the stiffness and viscoelasticity of native lung tissue

RHJ de Hilster, PK Sharma… - … of Physiology-Lung …, 2020 - journals.physiology.org
Chronic lung diseases such as idiopathic pulmonary fibrosis (IPF) and chronic obstructive
pulmonary disease (COPD) are associated with changes in extracellular matrix (ECM) …

Porcine lung-derived extracellular matrix hydrogel properties are dependent on pepsin digestion time

RA Pouliot, BM Young, PA Link, HE Park… - … Engineering Part C …, 2020 - liebertpub.com
Hydrogels derived from decellularized lungs are promising materials for tissue engineering
in the development of clinical therapies and for modeling the lung extracellular matrix (ECM) …

Decellularized extracellular matrix-based bio-ink with enhanced 3D printability and mechanical properties

MK Kim, W Jeong, SM Lee, JB Kim, S Jin… - Biofabrication, 2020 - iopscience.iop.org
Recently, decellularized extracellular matrix-based bio-ink (dECM bio-ink) derived from
animal organs is attracting attention because of its excellent biocompatibility. However, its …