Characteristics and pharmacological regulation of epithelial Na+ channel (ENaC) and epithelial Na+ transport
Y Marunaka - Journal of pharmacological sciences, 2014 - jstage.jst.go.jp
Epithelial Na+ transport participates in control of various body functions and conditions: eg,
homeostasis of body fluid content influencing blood pressure, control of amounts of fluids …
homeostasis of body fluid content influencing blood pressure, control of amounts of fluids …
[HTML][HTML] Regulation of Epithelial Sodium Transport via Epithelial Na+ Channel
Y Marunaka, N Niisato, A Taruno, M Ohta… - BioMed Research …, 2011 - hindawi.com
Renal epithelial Na+ transport plays an important role in homeostasis of our body fluid
content and blood pressure. Further, the Na+ transport in alveolar epithelial cells essentially …
content and blood pressure. Further, the Na+ transport in alveolar epithelial cells essentially …
Involvement of cytosolic Cl− in osmoregulation of α-ENaC gene expression
N Niisato, DC Eaton… - American Journal of …, 2004 - journals.physiology.org
Hypotonicity stimulates transepithelial Na+ reabsorption in renal A6 cells, but the
mechanism for this stimulation is not fully understood. In the present study, we found that …
mechanism for this stimulation is not fully understood. In the present study, we found that …
Hypotonicity stimulates renal epithelial sodium transport by activating JNK via receptor tyrosine kinases
A Taruno, N Niisato… - American Journal of …, 2007 - journals.physiology.org
We previously reported that hypotonic stress stimulated transepithelial Na+ transport via a
pathway dependent on protein tyrosine kinase (PTK; Niisato N, Van Driessche W, Liu M …
pathway dependent on protein tyrosine kinase (PTK; Niisato N, Van Driessche W, Liu M …
Regulation of an amiloride‐sensitive Na+‐permeable channel by a β2‐adrenergic agonist, cytosolic Ca2+ and Cl− in fetal rat alveolar epithelium
Y Marunaka, N Niisato, H O'Brodovich… - The Journal of …, 1999 - Wiley Online Library
1 In cell‐attached patches formed on the apical membrane of fetal alveolar epithelium,
terbutaline (a specific β2‐adrenergic agonist) increased the open probability (Po) of an …
terbutaline (a specific β2‐adrenergic agonist) increased the open probability (Po) of an …
Involvement of Protein Tyrosine Kinase in Osmoregulation of Na+ Transport and Membrane Capacitance in Renal A6 Cells
N Niisato, W Van Driessche, M Liu… - The Journal of Membrane …, 2000 - Springer
Renal A6 cells have been reported in which hyposmolality stimulates Na+ transport by
increasing the number of conducting amiloride-sensitive 4-pS Na+ channels at the apical …
increasing the number of conducting amiloride-sensitive 4-pS Na+ channels at the apical …
[HTML][HTML] Na+ homeostasis by epithelial Na+ channel (ENaC) and Nax channel (Nax): cooperation of ENaC and Nax
Y Marunaka, R Marunaka, H Sun… - Annals of …, 2016 - ncbi.nlm.nih.gov
The body fluid (extracellular fluid: ECF) volume is mainly regulated by Na+ uptake
(absorption) in the colon (1-3) and Na+ reabsorption in the kidney (4-7), and plays various …
(absorption) in the colon (1-3) and Na+ reabsorption in the kidney (4-7), and plays various …
Roles of Ca2+ and Protein Tyrosine Kinase in Insulin Action on Cell Volume via Na+ and K+ Channels and Na+/K+/2Cl− Cotransporter in Fetal Rat Alveolar Type …
The aim of the present study was to investigate the roles of Ca 2+ and protein tyrosine
kinase (PTK) in the insulin action on cell volume in fetal rat (20-day gestational age) type II …
kinase (PTK) in the insulin action on cell volume in fetal rat (20-day gestational age) type II …
The Essential Role of Cytosolic Cl− in Ca2+ Regulation of an Amiloride-Sensitive Channel in Fetal Rat Pneumocyte
Y Marunaka, N Niisato - The Journal of Membrane Biology, 2001 - Springer
An amiloride-sensitive, Ca 2+-activated nonselective cation (NSC) channel in the apical
membrane of fetal rat alveolar epithelium plays an important role in stimulation of Na+ …
membrane of fetal rat alveolar epithelium plays an important role in stimulation of Na+ …
[HTML][HTML] Membrane transport: ionic environments, signal transduction, and development of therapeutic targets
A Tomoda, Y Marunaka, DC Eaton… - BioMed Research …, 2015 - hindawi.com
Membrane transport plays a critical role in producing ionic environments in both intracellular
and extracellular spaces that are necessary for cellular signal transduction. The importance …
and extracellular spaces that are necessary for cellular signal transduction. The importance …