Fecal microbiota transplantation: in perspective

S Gupta, E Allen-Vercoe… - Therapeutic advances in …, 2016 - journals.sagepub.com
There has been increasing interest in understanding the role of the human gut microbiome
to elucidate the therapeutic potential of its manipulation. Fecal microbiota transplantation …

Population-level analysis of gut microbiome variation

G Falony, M Joossens, S Vieira-Silva, J Wang, Y Darzi… - Science, 2016 - science.org
Fecal microbiome variation in the average, healthy population has remained under-
investigated. Here, we analyzed two independent, extensively phenotyped cohorts: the …

The role of the gut microbiota in nutrition and health

HJ Flint, KP Scott, P Louis, SH Duncan - … reviews Gastroenterology & …, 2012 - nature.com
The microbial communities that colonize different regions of the human gut influence many
aspects of health. In the healthy state, they contribute nutrients and energy to the host via the …

[HTML][HTML] Sample storage conditions significantly influence faecal microbiome profiles

JM Choo, LEX Leong, GB Rogers - Scientific reports, 2015 - nature.com
Sequencing-based studies of the human faecal microbiota are increasingly common.
Appropriate storage of sample material is essential to avoid the introduction of post …

Faecalibacterium prausnitzii and human intestinal health

S Miquel, R Martin, O Rossi… - Current opinion in …, 2013 - Elsevier
Highlights•Faecalibacterium prausnitzii is an ubiquitary bacterium of intestinal microbiota of
all animals.•F. prausnitzii is a dominant member of human intestinal microbiota of healthy …

[HTML][HTML] Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

XC Morgan, TL Tickle, H Sokol, D Gevers, KL Devaney… - Genome biology, 2012 - Springer
Background The inflammatory bowel diseases (IBD) Crohn's disease and ulcerative colitis
result from alterations in intestinal microbes and the immune system. However, the precise …

Role of the gut microbiota in health and chronic gastrointestinal disease: understanding a hidden metabolic organ

CM Guinane, PD Cotter - Therapeutic advances in …, 2013 - journals.sagepub.com
The human gut microbiota has become the subject of extensive research in recent years and
our knowledge of the resident species and their potential functional capacity is rapidly …

[HTML][HTML] Understanding the holobiont: how microbial metabolites affect human health and shape the immune system

TS Postler, S Ghosh - Cell metabolism, 2017 - cell.com
The human gastrointestinal tract is populated by a diverse, highly mutualistic microbial flora,
which is known as the microbiome. Disruptions to the microbiome have been shown to be …

[HTML][HTML] Comparative microbiome signatures and short-chain fatty acids in mouse, rat, non-human primate, and human feces

R Nagpal, S Wang, LC Solberg Woods… - Frontiers in …, 2018 - frontiersin.org
Gut microbiome plays a fundamental role in several aspects of host health and diseases.
There has been an exponential surge in the use of animal models that can mimic different …

The gut microbiota in IBD

C Manichanh, N Borruel, F Casellas… - Nature reviews …, 2012 - nature.com
IBD—ulcerative colitis and Crohn's disease—is emerging as a worldwide epidemic. An
association between the increased incidence of IBD and environmental factors linked to …