Growing evidence has demonstrated that clonogenic cancer stem (initiating) cells are
responsible for tumor regrowth and disease relapse. Bmi‐1 plays a critical role in the self …

Endometrial cancer (EC) is the most common gynecologic malignancy of the female genital
tract and the fourth most common neoplasia in women. In EC, myometrial invasion is …

Background Epithelial-mesenchymal transition (EMT) is the key process driving cancer
metastasis. Oncogene/self renewal factor BMI-1 has been shown to induce EMT in cancer …

High grade serous ovarian carcinoma (HGSOC) is often diagnosed at an advanced stage.
Chromobox 2 (CBX2), a polycomb repressor complex subunit, plays an oncogenic role in …

Cancer stem-like cells exist in many malignancies and several stem cell-related genes and
microRNAs, such as Bmi-1 and miR-203, have been identified as cancer stem-like cell …

Metastasis and recurrence are the challenges of cancer therapy. Recently, mounting
evidence has suggested that cancer stem cells (CSCs) and epithelial-mesenchymal …

As with miRNAs a decade ago, the scientific community recently understood that lncRNAs
represent a new layer of complexity in the regulation of gene expression. Although only a …

Purpose: Epithelial ovarian cancer (EOC) is one of the most lethal gynecologic diseases,
with survival rate virtually unchanged for the past 30 years. EOC comprises different …

Aims miRNAs are small non-coding RNA molecules that regulate post-transcriptional gene
expression. Here we have made an endeavor to search whether any miRNAs are involved …

Background The purpose of present study was to examine the expression of cancer stem
cell marker Bmi-1 in breast cancer tissue and to evaluate the clinical implication of Bmi-1 …