Lipoprotein (a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement

F Kronenberg, S Mora, ESG Stroes… - European heart …, 2022 - academic.oup.com
Abstract This 2022 European Atherosclerosis Society lipoprotein (a)[Lp (a)] consensus
statement updates evidence for the role of Lp (a) in atherosclerotic cardiovascular disease …

Lipoprotein (a): a genetically determined, causal, and prevalent risk factor for atherosclerotic cardiovascular disease: a scientific statement from the American Heart …

G Reyes-Soffer, HN Ginsberg, L Berglund… - … , and vascular biology, 2022 - Am Heart Assoc
High levels of lipoprotein (a)[Lp (a)], an apoB100-containing lipoprotein, are an independent
and causal risk factor for atherosclerotic cardiovascular diseases through mechanisms …

[HTML][HTML] Lipoprotein (a) beyond the kringle IV repeat polymorphism: the complexity of genetic variation in the LPA gene

S Coassin, F Kronenberg - Atherosclerosis, 2022 - Elsevier
Abstract High lipoprotein (a)[Lp (a)] concentrations are one of the most important genetically
determined risk factors for cardiovascular disease. Lp (a) concentrations are an enigmatic …

Lipoprotein (a) and cardiovascular and valvular diseases: a genetic epidemiological perspective

BJ Arsenault, PR Kamstrup - Atherosclerosis, 2022 - Elsevier
Rates of atherosclerotic cardiovascular diseases (CVD) in the Western world have
spectacularly decreased over the past 50 years. However, a substantial proportion of high …

[HTML][HTML] Lipoprotein (a) measurement issues: are we making a mountain out of a molehill?

F Kronenberg - Atherosclerosis, 2022 - Elsevier
Abstract Lipoprotein (a)[Lp (a)] became besides LDL cholesterol one of the most attractive
targets for intervention in cardiovascular disease. Strong genetic evidence supports the …

Lipoprotein (a) and ethnicities

A Mehta, V Jain, A Saeed, JJ Saseen, M Gulati… - Atherosclerosis, 2022 - Elsevier
The initial studies focusing on lipoprotein (a)[Lp (a)] and its role in atherosclerotic
cardiovascular disease were conducted exclusively in Whites. Subsequently, multiple large …

[HTML][HTML] Frequent questions and responses on the 2022 lipoprotein (a) consensus statement of the European Atherosclerosis Society

F Kronenberg, S Mora, ESG Stroes, BA Ference… - Atherosclerosis, 2023 - Elsevier
Abstract In 2022, the European Atherosclerosis Society (EAS) published a new consensus
statement on lipoprotein (a)[Lp (a)], summarizing current knowledge about its causal …

Ancestry, Lipoprotein(a), and Cardiovascular Risk Thresholds: JACC Review Topic of the Week

S Tsimikas, SM Marcovina - Journal of the American College of Cardiology, 2022 - jacc.org
This study reviews ancestral differences in the genetics of the LPA gene, risk categories of
elevated lipoprotein (a)[Lp (a)] as defined by guidelines, ancestry-specific Lp (a) risk …

Clinical Trial Design for Lipoprotein(a)-Lowering Therapies: JACC Focus Seminar 2/3

WA Malick, SN Goonewardena, W Koenig… - Journal of the American …, 2023 - jacc.org
Abstract Lipoprotein (a)[Lp (a)] is a source of residual risk in patients with atherosclerotic
cardiovascular disease (ASCVD). Clinical trials of fully human monoclonal antibodies …

Lipoprotein (a): Knowns, unknowns and uncertainties

M Ruscica, CR Sirtori, A Corsini, GF Watts… - Pharmacological …, 2021 - Elsevier
Over the last 10 years, there have been advances on several aspects of lipoprotein (a)
which are reviewed in the present article. Since the standard immunoassays for measuring …