Integrins are transmembrane receptors that are central to the biology of many human
pathologies. Classically mediating cell-extracellular matrix and cell-cell interaction, and with …

Platelets are small anucleated cell fragments that ensure the arrest of bleeding after a vessel
wall injury. They are also involved in non-hemostatic function such as development …

Integrins are heterodimeric, transmembrane receptors that function as mechanosensors,
adhesion molecules and signal transduction platforms in a multitude of biological processes …

Platelet activation and coagulation normally do not occur in an intact blood vessel. After
blood vessel wall injury, platelet plug formation is initiated by the adherence of the platelets …

Cardiovascular diseases (CVDs) are considered as a major cause of death worldwide.
Therefore, identifying and developing therapeutic strategies to treat and reduce the …

Antiplatelet therapy plays a crucial role in a number of cardiovascular disorders. We
currently have a range of antiplatelet agents in our armamentarium. In this review, we aim to …

Background. Acute myocardial infarction (AMI) has been reported and is associated with
poor outcome in the course of thrombotic microangiopathies (TMA). However, data are very …

Platelets play a pivotal role in chronic inflammation leading to progression of atherosclerosis
and acute coronary events. Recent discoveries on novel mechanisms and platelet …

The utility of interventional cardiology has developed significantly over the last two decades
with the introduction of coronary angioplasty and stenting, with the associated antiplatelet …

Antiplatelet therapy is a cornerstone in the secondary prophylaxis of adverse cardiovascular
events such as myocardial infarction and stroke. The cyclooxygenase inhibitor aspirin …