Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Molecular mechanism of S-adenosylmethionine sensing by SAMTOR in mTORC1 signaling

X Tang, Y Zhang, G Wang, C Zhang, F Wang, J Shi… - Science …, 2022 - science.org
The mechanistic target of rapamycin–mLST8-raptor complex (mTORC1) functions as a
central regulator of cell growth and metabolism in response to changes in nutrient signals …

[HTML][HTML] Retinoic acid enhances ovarian steroidogenesis by regulating granulosa cell proliferation and MESP2/STAR/CYP11A1 pathway

S Cai, M Chen, B Xue, Z Zhu, X Wang, J Li… - Journal of Advanced …, 2024 - Elsevier
Introduction Ovarian steroidogenesis not only affects the embryonic development and
pregnancy outcome, but also associates with many diseases in mammals and women …

Chenodeoxycholic Acid Improves Embryo Implantation and Metabolic Health through Modulating Gut Microbiota–Host Metabolites Interaction during Early Pregnancy

M Chen, Y Zhao, H Ji, L Li, H Liu, S Wang, D Zhang… - Antioxidants, 2023 - mdpi.com
Fetus loss in early pregnancy is of major concern to both humans and animals, and this
issue is largely influenced by embryo implantation. Chenodeoxycholic acid (CDCA), a …

LINC02190 inhibits the embryo–endometrial attachment by decreasing ITGAD expression

F Zhao, T Chen, X Zhao, Q Wang, Y Lan… - …, 2022 - rep.bioscientifica.com
Recurrent implantation failure (RIF) is a challenge in the field of reproductive medicine, but
mechanisms for its occurrence remain still unclear. Long non-coding RNAs (lncRNAs) have …

Dietary methionine supplementation during the estrous cycle improves follicular development and estrogen synthesis in rats

G Yang, S Li, S Cai, J Zhou, Q Ye, S Zhang, F Chen… - Food & Function, 2024 - pubs.rsc.org
The follicle is an important unit for the synthesis of steroid hormones and the oocyte
development and maturation in mammals. However, the effect of methionine supply on …

[HTML][HTML] Uterine insulin sensitivity defects induced embryo implantation loss associated with mitochondrial dysfunction-triggered oxidative stress

M Chen, J Li, B Zhang, X Zeng, X Zeng, S Cai… - … Medicine and Cellular …, 2021 - hindawi.com
Scope. Implantation loss is a considerable cause of early pregnancy loss in humans and
mammalian animals. It is not addressed how proliferative uterine defects implicate in …

Molecular characterisation of uterine endometrial proteins during early stages of pregnancy in pigs by MALDI TOF/TOF

D Pierzchała, K Liput, A Korwin-Kossakowska… - International journal of …, 2021 - mdpi.com
The molecular mechanism underlying embryonic implantation is vital to understand the
correct communications between endometrium and developing conceptus during early …

Establishment and application of high throughput screening cell model for nutrient regulation of embryonic development

X Wang, J Huang, H Li, Y Li, S Cai, B Xue, Z Zhu… - The Journal of …, 2024 - Elsevier
Embryo development exerts far-reaching influence on pregnancy outcome, postnatal
development and lifelong health. Thereafter, to select functional nutrients to improve embryo …

Secretory Proteomic Responses of Endometrial Epithelial Cells to Trophoblast-Derived Extracellular Vesicles

S Muhandiram, K Dissanayake, T Orro… - International Journal of …, 2023 - mdpi.com
Synchronized crosstalk between the embryo and endometrium during the periconception
period is integral to pregnancy establishment. Increasing evidence suggests that the …