The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Cancer immunotherapy involves blocking the interactions between the PD-1/PD-L1 immune
checkpoints with antibodies. This has shown unprecedented positive outcomes in clinics …

Nanomaterials have garnered the significant interest of scientists owing to their
technological as well as medical applications. In particular, metal and metal oxide …

There is growing pressure for wastewater treatment plants to mitigate the discharge of
antibiotic resistant bacteria (ARB) and extracellular resistance genes (eARGs), which …

Plasmid DNA molecules with unique loop structures have widespread bioapplications, in
many cases relying heavily on delivery vehicles to introduce them into cells and achieve …

Nanoparticle based permeation enhancers have the potential to improve the oral delivery of
biologics. Recently, solid silica nanoparticles were discovered to improve the intestinal …

Periodontitis is recognized as the major cause of tooth loss in adults, posing an adverse
impact on systemic health. In periodontitis, excessive production of reactive oxygen species …

Abstract Natural two-dimensional (2D) kaolinite nanoclay has been incorporated into an
emerging drug delivery system. The basal spacing of the kaolinite nanoclay was expanded …

Inorganic nanoparticles have attracted much attentions in gene delivery because of their
desirable characteristics including low toxicity, well-controlled characteristics, high gene …

Advances in gene therapy have been foreshadowing its potential for the treatment of a vast
range of diseases involving genetic malfunctioning. However, its therapeutic efficiency and …