Next-generation sequencing technologies: An overview

T Hu, N Chitnis, D Monos, A Dinh - Human Immunology, 2021 - Elsevier
Since the days of Sanger sequencing, next-generation sequencing technologies have
significantly evolved to provide increased data output, efficiencies, and applications. These …

The interplay of long noncoding RNAs and hepatitis B virus

N Sarfaraz, S Somarowthu… - Journal of Medical …, 2023 - Wiley Online Library
Abstract Hepatitis B Virus (HBV) infections remain a major global health burden with an
estimated 296 million people living with a chronic infection and 884,000 HBV‐related deaths …

Bioaccumulation and reproductive effects of fluorescent microplastics in medaka fish

M Assas, X Qiu, K Chen, H Ogawa, H Xu… - Marine Pollution …, 2020 - Elsevier
This study was performed to elucidate the uptake and bioaccumulation of polystyrene
microplastics (PS-MPs) in Japanese medaka (freshwater fish) and Java medaka (marine …

deltaTE: detection of translationally regulated genes by integrative analysis of Ribo‐seq and RNA‐seq Data

S Chothani, E Adami, JF Ouyang… - Current protocols in …, 2019 - Wiley Online Library
Ribosome profiling quantifies the genome‐wide ribosome occupancy of transcripts. With the
integration of matched RNA sequencing data, the translation efficiency (TE) of genes can be …

[HTML][HTML] Variable selection for sparse data with applications to vaginal microbiome and gene expression data

N Dousti Mousavi, J Yang, H Aldirawi - Genes, 2023 - mdpi.com
Sparse data with a high portion of zeros arise in various disciplines. Modeling sparse high-
dimensional data is a challenging and growing research area. In this paper, we provide …

[HTML][HTML] Massive parallel alignment of rna-seq reads in serverless computing

P Cinaglia, JL Vázquez-Poletti… - Big Data and Cognitive …, 2023 - mdpi.com
In recent years, the use of Cloud infrastructures for data processing has proven useful, with a
computing potential that is not affected by the limitations of a local infrastructure. In this …

Farnesol brain transcriptomics in CNS inflammatory demyelination

WJ Doyle, D Walters, X Shi, K Hoffman, K Magori… - Clinical …, 2023 - Elsevier
Background Farnesol (FOL) prevents the onset of experimental autoimmune
encephalomyelitis (EAE), a murine model of multiple sclerosis (MS). Objective We examined …

Transcriptional responses and reduction in carpogenic germination of Sclerotinia sclerotiorum exposed to volatile organic compounds of Trichoderma azevedoi

LR da Silva, SCM de Mello, MC Valadares-Inglis… - Biological Control, 2022 - Elsevier
The disease caused by Sclerotinia sclerotiorum is known as white mold, sclerotic rot or
sclerotic wilt. The use of antagonistic fungi, such as those of the genus Trichoderma, has …

[HTML][HTML] Hydroxysafflor yellow a exerts neuroprotective effects via HIF-1α/BNIP3 pathway to activate neuronal autophagy after OGD/R

R Wei, L Song, Z Miao, K Liu, G Han, H Zhang, D Ma… - Cells, 2022 - mdpi.com
In the process of ischemic stroke (IS), cellular macroautophagy/autophagy and apoptosis
play a vital role in neuroprotection against it. Therefore, regulating their balance is a …

miR‐622 counteracts the NUAK1‐induced gastric cancer cell proliferation and the antioxidative stress

J Yang, J Lu, N Yin, J Sun, J Pu, J Zang - Disease Markers, 2022 - Wiley Online Library
Background. Gastric cancer (GC), a highly prevalent gastric cancer, has high‐risk mortality.
Thus, investigating strategies to counteract its growth is important to provide theoretical …