Modelling human placental villous development: designing cultures that reflect anatomy

JL James, A Lissaman, YNS Nursalim… - Cellular and Molecular …, 2022 - Springer
The use of in vitro tools to study trophoblast differentiation and function is essential to
improve understanding of normal and abnormal placental development. The relative …

Fetal growth restriction and stillbirth: Biomarkers for identifying at risk fetuses

VJ King, L Bennet, PR Stone, A Clark, AJ Gunn… - Frontiers in …, 2022 - frontiersin.org
Fetal growth restriction (FGR) is a major cause of stillbirth, prematurity and impaired
neurodevelopment. Its etiology is multifactorial, but many cases are related to impaired …

Neonatal encephalopathy and hypoxic–ischemic encephalopathy: moving from controversy to consensus definitions and subclassification

EJ Molloy, A Branagan, T Hurley, F Quirke… - Pediatric …, 2023 - nature.com
Neonatal encephalopathy (NE) is a “clinical syndrome of disturbed neurologic function in the
first week after birth in an infant born at or beyond 35 weeks of gestation, manifest by a …

Placenta-specific Slc38a2/SNAT2 knockdown causes fetal growth restriction in mice

OR Vaughan, K Maksym, E Silva, K Barentsen… - Clinical …, 2021 - portlandpress.com
Fetal growth restriction (FGR) is a complication of pregnancy that reduces birth weight,
markedly increases infant mortality and morbidity and is associated with later-life …

The effect of maternal position on placental blood flow and fetoplacental oxygenation in late gestation fetal growth restriction: a magnetic resonance imaging study

D Jani, A Clark, S Couper… - The Journal of …, 2023 - Wiley Online Library
Fetal growth restriction (FGR) and maternal supine going‐to‐sleep position are both risk
factors for late stillbirth. This study aimed to use magnetic resonance imaging (MRI) to …

Placental MRI predicts fetal oxygenation and growth rates in sheep and human pregnancy

D Flouri, JRT Darby, SL Holman, SKS Cho… - Advanced …, 2022 - Wiley Online Library
Magnetic resonance imaging (MRI) assessment of fetal blood oxygen saturation (SO2) can
transform the clinical management of high‐risk pregnancies affected by fetal growth …

The effects of maternal position, in late gestation pregnancy, on placental blood flow and oxygenation: an MRI study

S Couper, A Clark, JMD Thompson… - The Journal of …, 2021 - Wiley Online Library
Key points Maternal supine sleep position in late pregnancy is associated with an increased
risk of stillbirth. Maternal supine position in late pregnancy reduces maternal cardiac output …

[HTML][HTML] A review of feto-placental vasculature flow modelling

J Chappell, R Aughwane, AR Clark, S Ourselin… - Placenta, 2023 - Elsevier
The placenta provides the vital nutrients and removal of waste products required for fetal
growth and development. Understanding and quantifying the differences in structure and …

Advanced magnetic resonance imaging detects altered placental development in pregnancies affected by congenital heart disease

D Cromb, PJ Slator, M Hall, A Price, DC Alexander… - Scientific Reports, 2024 - nature.com
Congenital heart disease (CHD) is the most common congenital malformation and is
associated with adverse neurodevelopmental outcomes. The placenta is crucial for healthy …

[HTML][HTML] Data-Driven multi-Contrast spectral microstructure imaging with InSpect: INtegrated SPECTral component estimation and mapping

PJ Slator, J Hutter, RV Marinescu, M Palombo… - Medical image …, 2021 - Elsevier
We introduce and demonstrate an unsupervised machine learning technique for
spectroscopic analysis of quantitative MRI experiments. Our algorithm supports estimation of …