Epithelial-to-mesenchymal transition (EMT) and its reverse process MET naturally occur
during development and in tissue repair in vertebrates. EMT is also recognized as the …

Background The epithelial-mesenchymal transition (EMT) is crucial for metastasis and
positively regulated by calcium-related signaling. The melastatin-related transient receptor …

Triple-negative breast cancer (TNBC) accounts for 15% of overall breast cancer. A lack of
estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor …

Clear cell renal cell carcinoma (ccRCC) is a common genitourinary malignancy with high
mortality. However, the molecular pathogenesis of ccRCC remains unclear and effective …

Autophagy is an evolutionary conserved process mediating lysosomal degradation of
cytoplasmic material. Its involvement in cancer progression is highly controversial, due to its …

Epithelial–mesenchymal transition (EMT) is an essential mechanism contributing to
glioblastoma multiforme (GBM) progression, the most common and malignant brain tumor …

The main cause of death in cancer is the spread, or metastasis, of cancer cells to distant
organs with consequent tumor formation. Additionally, metastasis is a process that demands …

Background. Due to a lack of knowledge of the disease process, papillary renal cell
carcinoma (PRCC) has a dismal outlook. This research was aimed at uncovering the …

Cancerous tumors are the result of uncontrolled growth of cells. A growing body of evidence
points to cancer stem cells as being the genesis of this uncontrolled growth. Cancer stem …

GBMs (glioblastomas), or grade IV astrocytomas/gliomas, are the most frequent and
aggressive brain tumours, whose diagnosis and treatment is still inefficient. RTKs (receptor …