SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)
AD Proal, MB VanElzakker, S Aleman, K Bach… - Nature …, 2023 - nature.com
Millions of people are suffering from Long COVID or post-acute sequelae of COVID-19
(PASC). Several biological factors have emerged as potential drivers of PASC pathology …
(PASC). Several biological factors have emerged as potential drivers of PASC pathology …
Amyloid β-based therapy for Alzheimer's disease: Challenges, successes and future
Y Zhang, H Chen, R Li, K Sterling… - Signal transduction and …, 2023 - nature.com
Amyloid β protein (Aβ) is the main component of neuritic plaques in Alzheimer's disease
(AD), and its accumulation has been considered as the molecular driver of Alzheimer's …
(AD), and its accumulation has been considered as the molecular driver of Alzheimer's …
The neuroimmune axis of Alzheimer's disease
Alzheimer's disease (AD) is a genetically complex and heterogeneous disorder with
multifaceted neuropathological features, including β-amyloid plaques, neurofibrillary …
multifaceted neuropathological features, including β-amyloid plaques, neurofibrillary …
The gut microbiome in Alzheimer's disease: what we know and what remains to be explored
Abstract Alzheimer's disease (AD), the most common cause of dementia, results in a
sustained decline in cognition. There are currently few effective disease modifying therapies …
sustained decline in cognition. There are currently few effective disease modifying therapies …
The amyloid cascade hypothesis: an updated critical review
Results from recent clinical trials of antibodies that target amyloid-β (Aβ) for Alzheimer's
disease have created excitement and have been heralded as corroboration of the amyloid …
disease have created excitement and have been heralded as corroboration of the amyloid …
Mechanisms and pathology of protein misfolding and aggregation
Despite advances in machine learning-based protein structure prediction, we are still far
from fully understanding how proteins fold into their native conformation. The conventional …
from fully understanding how proteins fold into their native conformation. The conventional …
Role of gut-brain axis, gut microbial composition, and probiotic intervention in Alzheimer's disease
Gut microbiota represents a diverse and dynamic population of microorganisms harboring
the gastrointestinal tract, which influences the host health and disease. Gut microbiota …
the gastrointestinal tract, which influences the host health and disease. Gut microbiota …
The microbiota-gut-brain axis
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
The blood–brain barrier in health and disease: Important unanswered questions
CP Profaci, RN Munji, RS Pulido… - Journal of Experimental …, 2020 - rupress.org
The blood vessels vascularizing the central nervous system exhibit a series of distinct
properties that tightly control the movement of ions, molecules, and cells between the blood …
properties that tightly control the movement of ions, molecules, and cells between the blood …
The physiological roles of tau and Aβ: implications for Alzheimer's disease pathology and therapeutics
SA Kent, TL Spires-Jones, CS Durrant - Acta neuropathologica, 2020 - Springer
Tau and amyloid beta (Aβ) are the prime suspects for driving pathology in Alzheimer's
disease (AD) and, as such, have become the focus of therapeutic development. Recent …
disease (AD) and, as such, have become the focus of therapeutic development. Recent …