Hot topics in allergen immunotherapy, 2023: current status and future perspective
The importance of allergen immunotherapy (AIT) is multifaceted, encompassing both clinical
and quality‐of‐life improvements and cost‐effectiveness in the long term. Key mechanisms …
and quality‐of‐life improvements and cost‐effectiveness in the long term. Key mechanisms …
Allergen immunotherapy: progress and future outlook
L Šošić, M Paolucci, S Flory, F Jebbawi… - Expert Review of …, 2023 - Taylor & Francis
Introduction Allergy, the immunological hypersensitivity to innocuous environmental
compounds, is a global health problem. The disease triggers, allergens, are mostly proteins …
compounds, is a global health problem. The disease triggers, allergens, are mostly proteins …
Development of allergic rhinitis immunotherapy using antigen-loaded small extracellular vesicles
W Liu, M Ota, M Tabushi, Y Takahashi… - Journal of Controlled …, 2022 - Elsevier
Allergic rhinitis is caused by a breakdown of the Th1/Th2 balance, in which the allergen-
induced Th2 immune response predominates over the Th1 immune response, culminating …
induced Th2 immune response predominates over the Th1 immune response, culminating …
[HTML][HTML] Oral pretreatment with β-lactoglobulin derived peptide and CpG co-encapsulated in PLGA nanoparticles prior to sensitizations attenuates cow's milk allergy …
M Liu, S Thijssen, WE Hennink, J Garssen… - Frontiers in …, 2023 - frontiersin.org
Cow's milk allergy is a common food allergy among infants. Improved hygiene conditions
and loss of microbial diversity are associated with increased risk of allergy development …
and loss of microbial diversity are associated with increased risk of allergy development …
[HTML][HTML] Identification of robust biomarkers for early predicting efficacy of subcutaneous immunotherapy in children with house dust mite-induced allergic rhinitis by …
S Xie, R Fan, Q Tang, X Cai, H Zhang, F Wang… - Frontiers in …, 2022 - frontiersin.org
Background Subcutaneous immunotherapy (SCIT) is an effective treatment for children with
allergic rhinitis (AR), but its efficacy fluctuates among patients. There are no reliable …
allergic rhinitis (AR), but its efficacy fluctuates among patients. There are no reliable …
Engineering CpG‐ASO‐Pt‐Loaded Macrophages (CAP@ M) for Synergistic Chemo‐/Gene‐/Immuno‐Therapy
Adoptive cell therapy by natural cells for drug delivery has achieved encouraging progress
in cancer treatment over small‐molecule drugs. Macrophages have a great potential in …
in cancer treatment over small‐molecule drugs. Macrophages have a great potential in …
[HTML][HTML] Lacticaseibacillus paracasei GM-080 Ameliorates Allergic Airway Inflammation in Children with Allergic Rhinitis: From an Animal Model to a Double-Blind …
Background: Probiotics may facilitate the clinical management of allergic diseases.
However, their effects on allergic rhinitis (AR) remain unclear. We examined the efficacy and …
However, their effects on allergic rhinitis (AR) remain unclear. We examined the efficacy and …
[HTML][HTML] CpG ODN/Mangiferin Dual Delivery through Calcium Alginate Hydrogels Inhibits Immune-Mediated Osteoclastogenesis and Promotes Alveolar Bone …
Y Gu, Y Hu, S Huang, S Ruiz, T Kawai, Y Bai, X Han - Biology, 2023 - mdpi.com
Simple Summary The immune system plays an important role in the skeletal system during
bone repair and regeneration, especially in the oral environment with its constant host …
bone repair and regeneration, especially in the oral environment with its constant host …
ERK is involved in the regulation of CpG ODN 2395 on the expression levels of anti-lipopolysaccharide factors in Chinese mitten crab, Eriocheir sinensis
S Huang, Y Ma, F Wang, J Li, Z Yang, Y Jiang… - Fish & Shellfish …, 2022 - Elsevier
CpG oligodeoxynucleotides (ODN), as an effective adjuvant or immunopotentiator, activate
the immune system and induce various immune responses. Recently, it has also been …
the immune system and induce various immune responses. Recently, it has also been …
[HTML][HTML] Inhalative nanoparticulate cpg immunotherapy in severe equine asthma: an innovative therapeutic concept and potential animal model for human asthma …
Simple Summary Severe equine asthma is the most common globally widespread non-
infectious equine respiratory disease (together with its mild and moderate form), which is …
infectious equine respiratory disease (together with its mild and moderate form), which is …