Association of myelofibrosis phenotypes with clinical manifestations, molecular profiles, and treatments
HT Chifotides, S Verstovsek, P Bose - Cancers, 2023 - mdpi.com
Simple Summary Myelofibrosis is an aggressive bone marrow cancer whose clinical
presentation can be extremely heterogenous. Two distinct phenotypes, myeloproliferative …
presentation can be extremely heterogenous. Two distinct phenotypes, myeloproliferative …
BCR::ABL1-negative myeloproliferative neoplasms in the era of next-generation sequencing
A Mroczkowska-Bękarciak, T Wróbel - Frontiers in Genetics, 2023 - frontiersin.org
The classical BCR:: ABL1-negative myeloproliferative neoplasms such as polycythemia vera
(PV), essential thrombocythemia (ET), and myelofibrosis (MF) are clonal diseases with the …
(PV), essential thrombocythemia (ET), and myelofibrosis (MF) are clonal diseases with the …
The prognostic contribution of CBL, NRAS, KRAS, RUNX1, and TP53 mutations to mutation‐enhanced international prognostic score systems (MIPSS70/plus/plus …
GG Loscocco, G Rotunno, F Mannelli… - American Journal of …, 2024 - Wiley Online Library
Contemporary risk models in primary myelofibrosis (PMF) include the mutation (MIPSS70)
and mutation/karyotype enhanced (MIPSS70 plus/v2. 0) international prognostic scoring …
and mutation/karyotype enhanced (MIPSS70 plus/v2. 0) international prognostic scoring …
Neutrophil-to-lymphocyte ratio and all-cause mortality with and without myeloproliferative neoplasms—a Danish longitudinal study
MK Larsen, V Skov, L Kjær… - Blood Cancer …, 2024 - nature.com
The neutrophil-to-lymphocyte ratio (NLR) is increased in chronic inflammation and
myeloproliferative neoplasms (MPN). We hypothesize that NLR is associated with all-cause …
myeloproliferative neoplasms (MPN). We hypothesize that NLR is associated with all-cause …
Quantitative interpretation of bone marrow biopsies in MPN—What's the point in a molecular age?
The diagnosis of myeloproliferative neoplasms (MPN) requires the integration of clinical,
morphological, genetic and immunophenotypic findings. Recently, there has been a …
morphological, genetic and immunophenotypic findings. Recently, there has been a …
[HTML][HTML] Recent advances in therapies for primary myelofibrosis
W Vainchenker, N Yahmi, V Havelange, C Marty… - Faculty …, 2023 - ncbi.nlm.nih.gov
Primary myelofibrosis (PMF), polycythemia vera (PV) and essential thrombocythemia (ET)
form the classical BCR-ABL1-negative myeloproliferative neoplasms (MPNs) that are driven …
form the classical BCR-ABL1-negative myeloproliferative neoplasms (MPNs) that are driven …
Thrombopoietin, the primary regulator of platelet production: from mythos to logos, a thirty-year journey
K Kaushansky - Biomolecules, 2024 - mdpi.com
Thrombopoietin, the primary regulator of blood platelet production, was postulated to exist in
1958, but was only proven to exist when the cDNA for the hormone was cloned in 1994 …
1958, but was only proven to exist when the cDNA for the hormone was cloned in 1994 …
Myeloproliferative Neoplasms: Diseases Mediated by Chronic Activation of Signal Transducer and Activator of Transcription (STAT) Proteins
C Liongue, AC Ward - Cancers, 2024 - mdpi.com
Simple Summary A group of blood diseases called myeloproliferative neoplasms (MPNs)
cause a buildup of certain blood cell types in affected individuals. Each MPN category has a …
cause a buildup of certain blood cell types in affected individuals. Each MPN category has a …
Assessment of Total Antioxidant Capacity, 8-Hydroxy-2′-deoxy-guanosine, the Genetic Landscape, and Their Associations in BCR::ABL-1-Negative Chronic and …
Myeloproliferative neoplasms (MPNs), namely, polycythemia vera (PV), essential
thrombocythemia (ET), and primary myelofibrosis (PMF), are clonal stem cell disorders …
thrombocythemia (ET), and primary myelofibrosis (PMF), are clonal stem cell disorders …
The clinical relevance of broad mutational screening of myeloproliferative neoplasms at diagnosis
H Pettersson, J Adamsson, P Johansson… - Frontiers in …, 2023 - frontiersin.org
Introduction Myeloproliferative neoplasm (MPN) is a heterogenous group of hematological
malignancies including polycythemia vera (PV), essential thrombocythemia (ET) and …
malignancies including polycythemia vera (PV), essential thrombocythemia (ET) and …