Idiopathic pulmonary fibrosis: Current and future treatment

DS Glass, D Grossfeld, HA Renna… - The clinical …, 2022 - Wiley Online Library
Objectives Idiopathic pulmonary fibrosis (IPF) is a chronic fibrotic lung disease characterized
by dry cough, fatigue, and progressive exertional dyspnea. Lung parenchyma and …

Impact of antifibrotic therapy on mortality and acute exacerbation in idiopathic pulmonary fibrosis: a systematic review and meta-analysis

T Petnak, P Lertjitbanjong, C Thongprayoon, T Moua - Chest, 2021 - Elsevier
Background Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung
disease associated with significant morbidity and mortality. Nintedanib and pirfenidone are …

Geriatric nutritional risk index is a predictor of tolerability of antifibrotic therapy and mortality risk in patients with idiopathic pulmonary fibrosis

Y Mochizuka, Y Suzuki, M Kono, H Hasegawa… - …, 2023 - Wiley Online Library
Abstract Background and Objective Idiopathic pulmonary fibrosis (IPF) is characterized by
progressive lung fibrosis of unknown aetiology. Epidemiological studies have suggested …

Nutritional assessment in idiopathic pulmonary fibrosis: a prospective multicentre study

P Faverio, A Fumagalli, S Conti, F Madotto… - ERJ Open …, 2022 - Eur Respiratory Soc
Background Nutritional status impacts quality of life and prognosis of patients with
respiratory diseases, including idiopathic pulmonary fibrosis (IPF). However, there is a lack …

Contemporary concise review 2021: Interstitial lung disease

C McCarthy, MP Keane - Respirology, 2022 - Wiley Online Library
The last 2 years have presented previously unforeseen challenges in pulmonary medicine.
Despite the significant impact of the SARS‐CoV‐2 pandemic on patients, clinicians and …

Sarcopenia in idiopathic pulmonary fibrosis: a prospective study exploring prevalence, associated factors and diagnostic approach

P Faverio, A Fumagalli, S Conti, F Madotto, F Bini… - Respiratory …, 2022 - Springer
Background Sarcopenia gained importance in the evaluation of patients with chronic
respiratory diseases, including idiopathic pulmonary fibrosis (IPF), since it may impact …

Switching antifibrotics in patients with idiopathic pulmonary fibrosis: a multi-center retrospective cohort study

Y Suzuki, K Mori, Y Aono, M Kono, H Hasegawa… - BMC Pulmonary …, 2021 - Springer
Background Currently, there are two antifibrotics used to treat idiopathic pulmonary fibrosis
(IPF): pirfenidone and nintedanib. Antifibrotics slow disease progression by reducing the …

A systematic review of the prognostic significance of the body mass index in idiopathic pulmonary fibrosis

A Zinellu, C Carru, P Pirina, AG Fois… - Journal of Clinical …, 2023 - mdpi.com
The identification of novel prognostic biomarkers might enhance individualized
management strategies in patients with idiopathic pulmonary fibrosis (IPF). Although several …

Frequency and impact on clinical outcomes of sarcopenia in patients with idiopathic pulmonary fibrosis

K Fujita, H Ohkubo, A Nakano, Y Mori… - Chronic Respiratory …, 2022 - journals.sagepub.com
Objectives Sarcopenia is a syndrome characterized by reduced muscle mass and function. It
is well-recognized as a complication in chronic diseases such as chronic obstructive …

Dynapenia is highly prevalent in older patients with advanced idiopathic pulmonary fibrosis

M Bocchino, P Alicante, L Capitelli, AA Stanziola… - Scientific Reports, 2021 - nature.com
Body composition and muscle strength are emerging aspects in idiopathic pulmonary
fibrosis (IPF) clinical assessment. We aimed to study the relationships of handgrip strength …