Chirality plays an important role in the development of many pharmaceuticals, being a
general property of 'handedness'; nevertheless, a large number of pharmaceuticals are still …

Chronic kidney disease (CKD) is a progressive systemic disease, which changes the
function and structure of the kidneys irreversibly over months or years. The final common …

Stereoselective synthesis has been emerging as a resourceful tool because it enables the
obtaining of compounds with biological interest and high enantiomeric purity. Flavonoids are …

Rosemary (Rosmarinus officinalis L.) is one of the most famous spice plants belonging to the
Lamiaceae family as a remarkably beautiful horticultural plant and economically agricultural …

The plant diseases caused by a variety of pathogens such as viruses, bacteria and fungi
pose a great threat to global food production and food safety. Therefore, the search for …

Flavonoids are hydroxylated polyphenols that are widely distributed in plants with diverse
health benefits. Despite their popularity, the bioavailability of flavonoids is often overlooked …

Flavanone glucosides, such as naringin and neohesperidin, are present in specific Citrus
species and manifest a chiral center at the C-2 position of their flavanone moiety. This study …

Abstract The PI3K/AKT and MAPK/ERK pathways are frequently mutated in metastatic
melanoma. In a screen of over 2500 plant extracts, the dichloromethane extract of …

Enantiomeric separation of furanocoumarins and dihydroflavones compounds were
systematically studied in the normal‐phase mode using four different polysaccharide‐type …

In this study, the chiral separation of five flavanone glycosides was first examined on the
cellulose tris-(3, 5-dichlorophenylcarbamate)(CDCPC) chiral stationary phase (CSP) in the …