Atrial fibrillation (AF) constitutes an increasing health problem in the aging population.
Animal models reflecting human phenotypes are needed to understand the mechanisms of …

Abstract Cytochrome P4502J2 (CYP2J2) metabolizes arachidonic acid (AA) to
cardioprotective epoxyeicosatrienoic acids (EETs). Dronedarone, an antiarrhythmic drug …

Pharmacological inhibitors are frequently used to identify the receptors, receptor subtypes,
and associated signaling pathways involved in physiological cell responses. Based on the …

Amiodarone, one of the most widely prescribed antiarrhythmic drugs to treat both ventricular
and supraventricular arrhythmias, has been identified as a candidate drug for use against …

Thursday, February 25, 2021 227a mechanisms ranging from drug binding to specific sites,
over more non-specific drug-protein interactions, to drug-induced alteration of bilayer …

Amiodarone seems to exhibit some antiviral activity in the disease caused by SARS-CoV-2.
Here we have examined the SARS-CoV-2 disease course in the entire population of the …

Atrial fibrillation remains the most common arrhythmia in clinical practice. Dronedarone is an
antiarrhythmic drug for the maintenance of sinus rhythm in patients with atrial fibrillation …

We examined the inhibitory effect of amiodarone, a class III anti-arrhythmic agent, on voltage-
dependent K+(Kv) currents in freshly isolated rabbit coronary arterial smooth muscle cells …

Structure Activity Relationship forms the basis of Rational Drug Design in the circles of
pharmaceutical and medicinal chemistry. Appropriate knowledge of functional outcomes of …

Arzneimittelnebenwirkungen (UAW) sind ein häufig unterschätztes Problem der modernen
Medizin. In dieser Übersicht fassen wir häufige Nebenwirkungen der kardiovaskulären …