Tuning fatty acid oxidation in skeletal muscle with dietary fat and exercise
AM Fritzen, AM Lundsgaard, B Kiens - Nature Reviews Endocrinology, 2020 - nature.com
Both the consumption of a diet rich in fatty acids and exercise training result in similar
adaptations in several skeletal muscle proteins. These adaptations are involved in fatty acid …
adaptations in several skeletal muscle proteins. These adaptations are involved in fatty acid …
AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: implications for obesity
Skeletal muscle plays an important role in regulating whole-body energy expenditure given
it is a major site for glucose and lipid oxidation. Obesity and type 2 diabetes are causally …
it is a major site for glucose and lipid oxidation. Obesity and type 2 diabetes are causally …
[HTML][HTML] Perspective: a historical and scientific perspective of sugar and its relation with obesity and diabetes
Fructose-containing added sugars, such as sucrose and high-fructose corn syrup, have
been experimentally, epidemiologically, and clinically shown to be involved in the current …
been experimentally, epidemiologically, and clinically shown to be involved in the current …
Adipocyte signaling and lipid homeostasis: sequelae of insulin-resistant adipose tissue
YH Yu, HN Ginsberg - Circulation research, 2005 - Am Heart Assoc
For many years adipose tissue was viewed as the site where excess energy was stored, in
the form of triglycerides (TGs), and where that energy, when needed elsewhere in the body …
the form of triglycerides (TGs), and where that energy, when needed elsewhere in the body …
Obesity-related derangements in metabolic regulation
DM Muoio, CB Newgard - Annu. Rev. Biochem., 2006 - annualreviews.org
An epidemic surge in the incidence of obesity has occurred worldwide over the past two
decades. This alarming trend has been triggered by lifestyle habits that encourage …
decades. This alarming trend has been triggered by lifestyle habits that encourage …
Carbohydrate intake and obesity
RM Van Dam, JC Seidell - European journal of clinical nutrition, 2007 - nature.com
The prevalence of obesity has increased rapidly worldwide and the importance of
considering the role of diet in the prevention and treatment of obesity is widely …
considering the role of diet in the prevention and treatment of obesity is widely …
Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione …
GK Bandyopadhyay, JG Yu, J Ofrecio, JM Olefsky - Diabetes, 2006 - Am Diabetes Assoc
Increased accumulation of fatty acids and their derivatives can impair insulin-stimulated
glucose disposal by skeletal muscle. To characterize the nature of the defects in lipid …
glucose disposal by skeletal muscle. To characterize the nature of the defects in lipid …
Impaired muscle regeneration in ob/ob and db/db mice
MH Nguyen, M Cheng, TJ Koh - The Scientific World Journal, 2011 - Wiley Online Library
In obesity and type 2 diabetes, efficient skeletal muscle repair following injury may be
required, not only for restoring muscle structure and function, but also for maintaining …
required, not only for restoring muscle structure and function, but also for maintaining …
Intramuscular triacylglycerol and insulin resistance: guilty as charged or wrongly accused?
DM Muoio - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2010 - Elsevier
The term lipotoxicity elicits visions of steatotic liver, fat laden skeletal muscles and engorged
lipid droplets that spawn a number of potentially harmful intermediates that can wreak havoc …
lipid droplets that spawn a number of potentially harmful intermediates that can wreak havoc …
[HTML][HTML] Individual responses to completion of short-term and chronic interval training: a retrospective study
TA Astorino, MM Schubert - PloS one, 2014 - journals.plos.org
Alterations in maximal oxygen uptake (VO2max), heart rate (HR), and fat oxidation occur in
response to chronic endurance training. However, many studies report frequent incidence of …
response to chronic endurance training. However, many studies report frequent incidence of …