Matrix metalloproteinase in abdominal aortic aneurysm and aortic dissection

EM Maguire, SWA Pearce, R Xiao, AY Oo, Q Xiao - Pharmaceuticals, 2019 - mdpi.com
Abdominal Aortic Aneurysm (AAA) affects 4–5% of men over 65, and Aortic Dissection (AD)
is a life-threatening aortic pathology associated with high morbidity and mortality. Initiators of …

Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans

JB Michel, JL Martin-Ventura, J Egido… - Cardiovascular …, 2011 - academic.oup.com
Aneurysm of the abdominal aorta (AAA) is a particular, specifically localized form of
atherothrombosis, providing a unique human model of this disease. The pathogenesis of …

Abdominal aortic aneurysms

J Anagnostakos, BK Lal - Progress in cardiovascular diseases, 2021 - Elsevier
Abdominal aortic aneurysms (AAA) are prevalent among older adults and can cause
significant morbidity and mortality if not addressed in a timely fashion. Their etiology remains …

Tissue‐and Plasma‐Specific Micro RNA Signatures for Atherosclerotic Abdominal Aortic Aneurysm

K Kin, S Miyagawa, S Fukushima… - Journal of the …, 2012 - Am Heart Assoc
Background Atherosclerotic abdominal aortic aneurysm (AAA) is a progressive, gradual
aortic rupture that results in death in the absence of surgical intervention. Key factors that …

[HTML][HTML] Knockdown of lncRNA PVT1 inhibits vascular smooth muscle cell apoptosis and extracellular matrix disruption in a murine abdominal aortic aneurysm model

Z Zhang, G Zou, X Chen, W Lu, J Liu, S Zhai, G Qiao - Molecules and Cells, 2019 - Elsevier
This study was designed to determine the effects of the long non-coding RNA (lncRNA)
plasmacytoma variant translocation 1 (PVT1) on vascular smooth muscle cell (VSMC) …

Medical treatment for small abdominal aortic aneurysms

G Rughani, L Robertson… - Cochrane database of …, 2012 - cochranelibrary.com
Background Screening for abdominal aortic aneurysm (AAA) in selected groups is now
performed in England, the USA and Sweden. Patients with aneurysms over 55 mm in …

Upregulated signaling pathways in ruptured human saccular intracranial aneurysm wall: an emerging regulative role of Toll-like receptor signaling and nuclear factor …

MI Kurki, SK Häkkinen, J Frösen, R Tulamo… - …, 2011 - journals.lww.com
BACKGROUND: Aneurysmal subarachnoid hemorrhage, almost always from saccular
intracranial aneurysm (sIA), is a devastating form of stroke that affects the working-age …

Prevention of abdominal aortic aneurysm by Anti–MicroRNA-712 or Anti–MicroRNA-205 in angiotensin II–infused mice

CW Kim, S Kumar, DJ Son, IH Jang… - … , and vascular biology, 2014 - Am Heart Assoc
Objective—Abdominal aortic aneurysm (AAA) is characterized as a progressive dilation and
degradation of the aortic wall, associated with activation of matrix metalloproteinases …

Therapeutic potential of emerging NAD+-increasing strategies for cardiovascular diseases

N Rotllan, M Camacho, M Tondo, EMG Diarte-Añazco… - Antioxidants, 2021 - mdpi.com
Cardiovascular diseases are the leading cause of death worldwide. Aging and/or metabolic
stress directly impact the cardiovascular system. Over the last few years, the contributions of …

The contribution of matrix metalloproteinases and their inhibitors to the development, progression, and rupture of abdominal aortic aneurysms

G Atkinson, R Bianco, K Di Gregoli… - Frontiers in …, 2023 - frontiersin.org
Abdominal aortic aneurysms (AAAs) account for up to 8% of deaths in men aged 65 years
and over and 2.2% of women. Patients with AAAs often have atherosclerosis, and intimal …