[HTML][HTML] Biosafety of mesoporous silica nanoparticles; towards clinical translation

A Lérida-Viso, A Estepa-Fernández… - Advanced Drug Delivery …, 2023 - Elsevier
Mesoporous silica nanoparticles (MSNs) have attracted the attention of chemists, who have
developed numerous systems for the encapsulation of a plethora of molecules, allowing the …

[HTML][HTML] Mesoporous silica nanoparticles for therapeutic/diagnostic applications

S Jafari, H Derakhshankhah, L Alaei, A Fattahi… - Biomedicine & …, 2019 - Elsevier
Based on unique intrinsic properties of mesoporous silica nanoparticles (MSNs) such as
high surface area, large pore size, good biocompatibility and biodegradability, stable …

Nanomaterials for theranostics: recent advances and future challenges

EK Lim, T Kim, S Paik, S Haam, YM Huh… - Chemical reviews, 2015 - ACS Publications
In 2004, the US Food and Drug Administration (FDA) released an important report entitled
“Innovation/Stagnation: Challenge and Opportunity on the Critical Path to New Medical …

Mesoporous silica nanoparticles: synthesis, classification, drug loading, pharmacokinetics, biocompatibility, and application in drug delivery

Z Li, Y Zhang, N Feng - Expert opinion on drug delivery, 2019 - Taylor & Francis
ABSTRACT Introduction: Mesoporous silica nanoparticles (MSNs) feature a high surface
area and large pore volume, uniform and tunable pore size, and stable framework; thus, they …

Fluorescent probes for pH and alkali metal ions

W Chen, X Ma, H Chen, SH Liu, J Yin - Coordination Chemistry Reviews, 2021 - Elsevier
The homeostasis of acid/base and alkali metal played critical roles in life process. To get
insight into their functional mechanism, a large amount of detectors, especially based on …

Chemistry, biology, and medicine of fluorescent nanomaterials and related systems: new insights into biosensing, bioimaging, genomics, diagnostics, and therapy

J Yao, M Yang, Y Duan - Chemical reviews, 2014 - ACS Publications
2. INTRODUCTION The investigation of many fundamental processes in life sciences
requires straightforward tools for fast, sensitive, reliable, and reproducible detection of …

[HTML][HTML] Indocyanine green-incorporating nanoparticles for cancer theranostics

H Wang, X Li, BWC Tse, H Yang, CA Thorling, Y Liu… - Theranostics, 2018 - ncbi.nlm.nih.gov
Indocyanine green (ICG) is a near-infrared dye that has been used in the clinic for retinal
angiography, and defining cardiovascular and liver function for over 50 years. Recently …

Multifunctional mesoporous silica nanoparticles as a universal platform for drug delivery

C Argyo, V Weiss, C Bräuchle, T Bein - Chemistry of materials, 2014 - ACS Publications
Nanosized mesoporous silica particles with high colloidal stability attract growing attention
as drug delivery systems for targeted cancer treatment and as bioimaging devices. This …

A review of NIR dyes in cancer targeting and imaging

S Luo, E Zhang, Y Su, T Cheng, C Shi - Biomaterials, 2011 - Elsevier
The development of multifunctional agents for simultaneous tumor targeting and near
infrared (NIR) fluorescence imaging is expected to have significant impact on future …

In vivo bio‐safety evaluations and diagnostic/therapeutic applications of chemically designed mesoporous silica nanoparticles

Y Chen, H Chen, J Shi - Advanced Materials, 2013 - Wiley Online Library
The remarkable progress of nanotechnology and its application in biomedicine have greatly
expanded the ranges and types of biomaterials from traditional organic material‐based …