Inflammatory bowel diseases are inflammatory, chronic and progressive diseases of the
intestinal tract for which no curative treatment is available. Research in other fields with stem …

Background Adult intestinal organoids have been used to study ex vivo intestinal injury in
adulthood. However, the neonatal intestinal epithelium has many unique features that are …

Necrotizing enterocolitis (NEC) is characterized by intestinal inflammation and in severe
cases, necrosis and perforation. It remains an unsolved clinical challenge with mortality …

For repair of chronic or difficult-to-heal tissue lesions and defects, major constraints exist to a
broad application of cell therapy and tissue engineering approaches, ie, transplantation of …

Congenital diseases are responsible for over a third of all pediatric hospital admissions.
Advances in prenatal screening and molecular diagnosis have allowed the detection of …

Necrotizing enterocolitis (NEC) is a major cause of morbidity and mortality in premature
infants. NEC is characterized by intestinal tissue inflammation and necrosis. The intestinal …

We previously reported that c-KIT+ human amniotic-fluid derived stem cells obtained from
leftover samples of routine II trimester prenatal diagnosis (fetal hAFS) are endowed with …

Necrotizing enterocolitis (NEC) is the most common life threatening condition affecting
preterm infants. NEC occurs in 1–5% of all neonatal intensive care admissions and 5–10 …

Background Despite emergence of markers of intestinal mucosal damage such as intestinal
fatty-acid binding protein (i-FABP), there are no specific markers of damage extending into …

Regenerative medicine has become an emerging field which focuses on repair,
replacement or regeneration of cells, tissues and the entire organs. The regeneration may …