Mesenchymal stem cells and their microenvironment

J Liu, J Gao, Z Liang, C Gao, Q Niu, F Wu… - Stem Cell Research & …, 2022 - Springer
Mesenchymal stem cells (MSCs), coming from a wide range of sources, have multi-
directional differentiation ability. MSCs play vital roles in immunomodulation, hematopoiesis …

Mechanisms behind therapeutic potentials of mesenchymal stem cell mitochondria transfer/delivery

K Malekpour, A Hazrati, S Soudi… - Journal of Controlled …, 2023 - Elsevier
Mesenchymal stromal/stem cells (MSCs) perform their therapeutic effects through various
mechanisms, including their ability to differentiate, producing different growth factors …

Gene therapy based on mesenchymal stem cells derived from adipose tissue for the treatment of obesity and its metabolic complications

M Lopez-Yus, MP García-Sobreviela… - International Journal of …, 2023 - mdpi.com
Obesity is a highly prevalent condition often associated with dysfunctional adipose tissue.
Stem cell-based therapies have become a promising tool for therapeutic intervention in the …

[HTML][HTML] Differential dynamics of bone graft transplantation and mesenchymal stem cell therapy during bone defect healing in a murine critical size defect

EE Huang, N Zhang, EA Ganio, H Shen, X Li… - Journal of Orthopaedic …, 2022 - Elsevier
Background A critical size bone defect is a clinical scenario in which bone is lost or excised
due to trauma, infection, tumor, or other causes, and cannot completely heal spontaneously …

[HTML][HTML] Magnetic nanoparticles and magnetic field exposure enhances chondrogenesis of human adipose derived mesenchymal stem cells but not of Wharton jelly …

L Labusca, DD Herea, A Emanuela Minuti… - … in Bioengineering and …, 2021 - frontiersin.org
Purpose: Iron oxide based magnetic nanoparticles (MNP) are versatile tools in biology and
medicine. Adipose derived mesenchymal stem cells (ADSC) and Wharton Jelly …

Thermo-responsive gel containing hydroxytyrosol-chitosan nanoparticles (Hyt@ tgel) counteracts the increase of osteoarthritis biomarkers in human chondrocytes

A Valentino, R Conte, I De Luca, F Di Cristo, G Peluso… - Antioxidants, 2022 - mdpi.com
Although osteoarthritis (OA) is a chronic inflammatory degenerative disease affecting
millions of people worldwide, the current therapies are limited to palliative care and do not …

Extracellular matrix microparticles improve GelMA bioink resolution for 3D bioprinting at ambient temperature

Z Galliger, CD Vogt, HR Helms… - Macromolecular …, 2022 - Wiley Online Library
Introduction: Current bioinks for 3D bioprinting, such as gelatinmethacryloyl, are generally
low viscosity fluids at room temperature, requiring specialized systems to create complex …

[HTML][HTML] 3D printing of high-strength photo-crosslinking flaxseed gum bioink for cartilage regeneration

K Shu, Z Huang, X Pei, PYM Yew, S Wei, Y Yang… - Composites Part B …, 2023 - Elsevier
Abstract Three-dimensional (3D) bioprinting provides a new possibility for personal
customization of cartilage tissues. Although biocompatible, most natural biopolymer inks …

Assessment of the Efficacy of Bone MarrowDerived Mesenchymal Stem Cells against a MonoiodoacetateInduced Osteoarthritis Model in Wistar Rats

HM Hamdalla, RR Ahmed, SR Galaly… - Stem Cells …, 2022 - Wiley Online Library
Osteoarthritis (OA) of the knee is a debilitating condition that can severely limit an
individual's mobility and quality of life. This study was designed to evaluate the efficacy of …

Primary MSCs for personalized medicine: ethical challenges, isolation and biocompatibility evaluation of 3D electrospun and printed scaffolds

AM Feier, D Portan, DR Manu, V Kostopoulos… - Biomedicines, 2022 - mdpi.com
Autologous cell therapy uses patients' own cells to deliver precise and ideal treatment
through a personalized medicine approach. Isolation of patients' cells from residual tissue …