Piezo1 channels as force sensors in mechanical force-related chronic inflammation

H Liu, J Hu, Q Zheng, X Feng, F Zhan, X Wang… - Frontiers in …, 2022 - frontiersin.org
Mechanical damage is one of the predisposing factors of inflammation, and it runs through
the entire inflammatory pathological process. Repeated or persistent damaging mechanical …

Pulmonary surfactant: A mighty thin film

F Possmayer, YY Zuo, RAW Veldhuizen… - Chemical …, 2023 - ACS Publications
Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …

Amyloid-Forming Corpora Amylacea and Spheroid-Type Amyloid Deposition: Comprehensive Analysis Using Immunohistochemistry, Proteomics, and a Literature …

S Ichimata, Y Hata, T Yoshinaga, N Katoh… - International Journal of …, 2024 - mdpi.com
This study aimed to elucidate the similarities and differences between amyloid-forming
corpora amylacea (CA) in the prostate and lung, examine the nature of CAs in cystic tumors …

[PDF][PDF] HUB genes transcriptionally regulate lipid metabolism in alveolar type II cells under LPS stimulation

X Chen, C Xiao, Y Liu, Q Li, Y Cheng, S Li, W Li… - Heliyon, 2023 - cell.com
Abstract Objective Alveolar type II (ATII) cells produce pulmonary surfactant (PS) essential
for maintaining lung function. The aberration or depletion of PS can cause alveolar collapse …

Preterm birth affects both surfactant synthesis and lung liquid resorption actors in fetal sheep

L Orlandi, Y Rodriguez, A Leostic, C Giraud… - Developmental …, 2024 - Elsevier
Introduction After birth, the lungs must resorb the fluid they contain. This process involves
multiple actors such as surfactant, aquaporins and ENaC channels. Preterm newborns often …

Bovine pulmonary surfactant alleviates inflammation and epithelial cell apoptosis in the early phase of lipopolysaccharide-induced acute lung injury in rats

X Chen, JS Dumbuya, J Du, L Xue… - … and Genetic Engineering …, 2023 - Taylor & Francis
We investigate the impact of bovine pulmonary surfactant (PS) on LPS-induced ALI in vitro
and in vivo to improve recognition and prevent mortality in sepsis-induced ALI. Primary …

[HTML][HTML] Commonly used medications for respiratory and cardiovascular support in neonates: Evidence, knowledge gaps, and future perspectives

E Agakidou, A Kontou, E Chatziioannidis, W Chotas… - Global Pediatrics, 2024 - Elsevier
Critically ill neonates admitted to neonatal intensive care units require specialized
pharmacological treatment due to various medical conditions. However, despite the …

Targeted biologics: the new frontier for precision therapy

S Bruno, PW Buehler… - Current Medicinal …, 2022 - ingentaconnect.com
Functionalized antibodies, protein substitution, supplementation therapies, and enzyme-
based therapeutics are protein-based approaches for the treatment and cure of human …

[HTML][HTML] Lung surfactant as a biophysical assay for inhalation toxicology

JY Liu, CM Sayes - Current Research in Toxicology, 2023 - Elsevier
Lung surfactant (LS) is a mixture of lipids and proteins that forms a thin film at the gas-
exchange surfaces of the alveoli. The components and ultrastructure of LS contribute to its …

Surfactants-surface active agents behind sustainable living

P Jayasankar, R KarthyayaniAmma - Physical Sciences Reviews, 2024 - degruyter.com
Abstract Surfactants<? index value=" Surfactants"?> are surface active agents. They are
mainly chemicals, when added to water will reduce the surface tension<? index value=" …