During fertilization, the egg and the sperm are supposed to contribute precisely one copy of
each chromosome to the embryo. However, human eggs frequently contain an incorrect …

Polycystic ovarian syndrome (PCOS) is a prevailing endocrine and metabolic disorder
occurring in about 6–20% of females in reproductive age. Most symptoms of PCOS arise …

Ovarian fibrosis is a pathological condition associated with aging and is responsible for a
variety of ovarian dysfunctions. Given the known contributions of tissue fibrosis to …

Background Hormones and immune imbalance are critical factors in polycystic ovary
syndrome (PCOS). The alternation of immune microenvironment of oocytes may play a …

Simple Summary Ovarian high-grade serous carcinoma (HGSC) has a 5-year survival rate
of less than 50%, making it one of the most lethal gynecological cancers for women in the …

Normal levels of reactive oxygen species (ROS) play an important role in regulating follicular
growth, angiogenesis and sex hormone synthesis in ovarian tissue. When the balance …

Progressive loss of physiological integrity and accumulation of degenerative changes
leading to functional impairment and increased susceptibility to diseases are the main …

The potential for repeated ovulation and menstruation is thought to have provided a
Darwinian advantage during the Palaeolithic. Reproductive conditions remained relatively …

The estrous cycle is regulated by rhythmic endocrine interactions of the nervous and
reproductive systems, which coordinate the hormonal and ovulatory functions of the ovary …

Both depression and sleep disturbance have been linked to inflammation. However, the role
that inflammation plays in the relationship between sleep disturbance and depression …