The oldest known highly conserved modification of RNA, N4-acetylcytidine, is widely
distributed from archaea to eukaryotes and acts as a posttranscriptional chemical …

In vitro maturation (IVM) of oocytes is a promising assisted reproductive technology (ART)
deemed as a simple and safe procedure. It is mainly used in patients with impaired oocyte …

Regulation of the epigenome is a mechanism by which the environment influences gene
expression and consequently the health of the individual. The advent and refinement of …

Sometimes, for medical reasons, when a frozen tissue has already thawed, an operation by
re-transplantation may be cancelled, and ovarian tissues should be re-frozen for …

Since the announcement of the birth of Dolly, the world's first mammal produced by cloning,
it was demonstrated for the first time that somatic cells could be reprogrammed to produce a …

To explore the mechanisms leading to the poor quality of IVF blastocysts, the single-cell
whole-genome methylation sequencing technique was used in this study to analyse the …

Infertility in humans at their reproductive age is a world-wide problem. Oocyte in vitro
maturation (IVM) is generally used in such cases to acquire the embryo in assisted …

Purpose Epigallocatechin-3-gallate (EGCG) is a major ingredient of catechin polyphenols
and exerts protective effects because of its strong antioxidant properties. As far as we know …

We report a case of ultrasound-guided ex vivo oocyte retrieval for fertility preservation in a
woman with bilateral borderline ovarian tumor, for whom conventional transvaginal oocyte …

Small RNA molecules in early embryos, delivered from sperm to zygotes upon fertilization,
are required for normal mouse embryonic development. Even modest changes in the levels …