The principles of the rational pharmacotherapy in pediatric practice are generalized. It
should take into account characteristics of pharmacokinetic and pharmacodynamic of drugs …

Objectives To explore the views and perspectives of children on the unlicensed/off-label use
of medicines in children and on the participation of children in clinical trials. Methods Focus …

Background: Knowledge of drugs safety collected during the pre-marketing phase is
inevitably limited because the randomized clinical trials (RCTs) are rarely designed to …

Con el objetivo de destacar la importancia de la farmaco vigilancia en pediatría, se efectuó
una revisión con especial énfasis en sus aspectos generales y conceptuales, sustentados …

Background The prescribing of psychotropic medicines for the paediatric population is
rapidly increasing. In attempts to curb the use of psychotropic medicine in the paediatric …

Systemic antibiotics are the group of drugs most commonly used in children. Off-label
antibiotic use in children is still common in the community and in hospitals, mostly because …

Little is known about factors that affect pharmacists' roles in off-label prescribing. This study
examined the effect of perceived impact on relationship quality (IRQ) on hospital …

Background: Regulatory bodies including the European Medicines Agency register
medications (formulation, route of administration) for specific clinical indications. Once …

Adverse drug reactions (ADRs) are an important clinical problem and contribute significantly
to mortality and morbidity. Scant data on the safety of drug use in children are usually …

Muchos estudios han descrito la mayor susceptibilidad pediátrica a la aparición de errores;
los niños son especialmente vulnerables, por lo que corresponde extremar la vigilancia …