Interstitial lung damage due to cocaine abuse: pathogenesis, pharmacogenomics and therapy

M Drent, P Wijnen, A Bast - Current medicinal chemistry, 2012 - ingentaconnect.com
Medicinal agents, beside occupational and environmental agents, remain one of the most
common causes for interstitial lung diseases (ILD). A major problem with ILD is the …

Effect of long-term administration of amiodarone on rat lung and the possible protective role of vitamin E: a histological and immunohistochemical study

RA Zidan - Egyptian Journal of Histology, 2011 - journals.lww.com
Objective This study was undertaken to investigate the effect of long-term amiodarone
administration and withdrawal on the histological structure of rat lung. In addition, the …

[HTML][HTML] Human placental extract ameliorates structural lung changes Iinduced by Amiodarone in rats

F Samiei, A Jamshidzadeh, A Noorafshan… - Iranian journal of …, 2016 - ncbi.nlm.nih.gov
Amiodarone is used in treatment of cardiac arrhythmias. Therapeutic use of amiodarone is
limited by its side effects, including pulmonary toxicity. Human Placenta Extract (HPE) …

Biochemical and ultrastructural lung damage induced by rhabdomyolysis in the rat

R Rodrigo, S Trujillo, C Bosco - Experimental Biology and …, 2006 - journals.sagepub.com
Rhabdomyolysis-induced oxidative stress is associated with morphological and functional
damage to the kidney and other organs, but applications of this model in the lung are still …

[PDF][PDF] Amiodarone-induced lung toxicity and the protective role of Vitamin E in adult male albino rat

FAER Gawad, AAEE Rizk, MF Jouakim… - Eur J …, 2018 - researchgate.net
Amiodarone is a highly effective anti-arrhythmic drug, used in the treatment of cardiac
arrhythmias. However, it is of a limited use due its serious side effects especially lung …

Direct mitochondrial dysfunction precedes reactive oxygen species production in amiodarone-induced toxicity in human peripheral lung epithelial HPL1A cells

AC Nicolescu, Y Ji, JL Comeau, BC Hill… - Toxicology and applied …, 2008 - Elsevier
Amiodarone (AM), a drug used in the treatment of cardiac dysrrhythmias, can produce
severe pulmonary adverse effects, including fibrosis. Although the pathogenesis of AM …

[HTML][HTML] Effect of Aronia melanocarpa fruit juice on amiodarone-induced pneumotoxicity in rats

S Valcheva-Kuzmanova, G Stavreva… - Pharmacognosy …, 2014 - ncbi.nlm.nih.gov
Background: The fruits of Aronia melanocarpa (Michx.) Elliot is extremely rich in biologically
active polyphenols. Objective: We studied the protective effect of A. melanocarpa fruit juice …

Aryl radical involvement in amiodarone-induced pulmonary toxicity: investigation of protection by spin-trapping nitrones

AC Nicolescu, JL Comeau, BC Hill, LL Bedard… - Toxicology and applied …, 2007 - Elsevier
Amiodarone (AM), an antidysrrhythmic drug, can produce serious adverse effects, including
potentially fatal AM-induced pulmonary toxicity (AIPT). AM-induced cytotoxicity and …

The possible effects of α-tocopherol against amiodarone-treated lungs in rats: vimentin detection, lipid peroxidation assay, and histological and ultrastructural …

MSA Zaki, AF El-Kott, HIM AlGwaiz, SF Shehata… - … Science and Pollution …, 2022 - Springer
The purpose of this study was to learn more about the pathogenesis of amiodarone (AD) on
alveoli and also the possible preventive effect of α-tocopherol (α-T) against these hazards …

Methanolic extract of Moringa oleifera leaf and low doses of gamma radiation alleviated amiodarone-induced lung toxicity in albino rats

H Hasan, NM Thabet… - Archives of Biological …, 2016 - serbiosoc.org.rs
This study aimed to evaluate the effects of methanolic extract of Moringa oleifera (MO)
and/or low doses of gamma radiation (LDR) on amiodarone (AMD)-induced lung toxicity in …