Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): a systemic infection

A Synowiec, A Szczepański… - Clinical microbiology …, 2021 - Am Soc Microbiol
To date, seven identified coronaviruses (CoVs) have been found to infect humans; of these,
three highly pathogenic variants have emerged in the 21st century. The newest member of …

[HTML][HTML] A rapid review of recent advances in diagnosis, treatment and vaccination for COVID-19

S Umakanthan, VK Chattu, AV Ranade, D Das… - AIMS Public …, 2021 - ncbi.nlm.nih.gov
COVID-19 is caused by SARS-CoV-2, which originated in Wuhan, Hubei province, Central
China, in December 2019 and since then has spread rapidly, resulting in a severe …

[HTML][HTML] Covid-19-associated coagulopathy: biomarkers of thrombin generation and fibrinolysis leading the outcome

M Ranucci, C Sitzia, E Baryshnikova… - Journal of clinical …, 2020 - mdpi.com
Background: Coronavirus Disease 2019 (COVID-19)-associated coagulopathy is
characterized by a prothrombotic state not yet comprehensively studied. We investigated the …

[HTML][HTML] Drugs for COVID-19: An update

J Ceramella, D Iacopetta, MS Sinicropi, I Andreu… - Molecules, 2022 - mdpi.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was the seventh
known human coronavirus, and it was identified in Wuhan, Hubei province, China, in 2020. It …

A comprehensive guide to the pharmacologic regulation of angiotensin converting enzyme 2 (ACE2), the SARS-CoV-2 entry receptor

M Oz, DE Lorke, N Kabbani - Pharmacology & therapeutics, 2021 - Elsevier
The recent emergence of coronavirus disease-2019 (COVID-19) as a global pandemic has
prompted scientists to address an urgent need for defining mechanisms of disease …

Long-chain polyphosphates impair SARS-CoV-2 infection and replication

V Ferrucci, DY Kong, F Asadzadeh, L Marrone… - Science …, 2021 - science.org
Inorganic polyphosphates (polyPs) are linear polymers composed of repeated phosphate
(PO43−) units linked together by multiple high-energy phosphoanhydride bonds. In addition …

Systematic review and meta-analysis of the prevalence of venous thromboembolic events in novel coronavirus disease-2019 patients

R Zhang, L Ni, X Di, X Wang, B Ma, S Niu… - Journal of Vascular …, 2021 - Elsevier
Background Emerging clinical evidence has shown that patients with the novel coronavirus
disease-2019 (COVID-19) have complications that include venous thromboembolism (VTE) …

[HTML][HTML] Occurrence, fate, effects, and risks of dexamethasone: Ecological implications post-COVID-19

N Musee, LP Kebaabetswe, S Tichapondwa… - International journal of …, 2021 - mdpi.com
The recent outbreak of respiratory syndrome-coronavirus-2 (SARS-CoV-2), which causes
coronavirus disease (COVID-19), has led to the widespread use of therapeutics, including …

AIEgen‐enhanced protein imaging: Probe design and sensing mechanisms

S Naghibi, T Chen, A Jamshidi Ghahfarokhi… - Aggregate, 2021 - Wiley Online Library
Proteins are the building blocks of life, regarded as one of the most complex and crucial
biomacromolecules in biological systems, and playing a significant role in executing genes …

[HTML][HTML] Heparin and its derivatives: challenges and advances in therapeutic biomolecules

N Banik, SB Yang, TB Kang, JH Lim, J Park - International journal of …, 2021 - mdpi.com
Heparin has been extensively studied as a safe medicine and biomolecule over the past few
decades. Heparin derivatives, including low-molecular-weight heparins (LMWH) and …