Itch is one of the most primal sensations, being both ubiquitous and important for the well-
being of animals. For more than a century, a desire to understand how itch is encoded by the …

Atopic dermatitis (AD) is a chronic, heterogenous, inflammatory skin disorder associated
with a high skin‐related health burden, typically starting in childhood and often persisting …

Tissue immunity and responses to injury depend on the coordinated action and
communication among physiological systems. Here, we show that, upon injury, adaptive …

Food is simultaneously a source of essential nutrients and a potential source of lethal toxins
and pathogens. Consequently, multiple sensory mechanisms evolved to monitor the quality …

Itch is an unpleasant sensation that evokes a desire to scratch. The skin barrier is constantly
exposed to microbes and their products. However, the role of microbes in itch generation is …

Background Chronic pruritus, or itch, is common and debilitating, but the neuro-immune
mechanisms that drive chronic itch are only starting to be elucidated. Recent studies …

Food allergy (FA) is now one of the most common chronic diseases of childhood often
lasting throughout life and leading to significant worldwide healthcare burden. The precise …

Gastrin releasing peptide receptor (GRPR), a member of the bombesin (BBN) G protein-
coupled receptors, is aberrantly overexpressed in several malignant tumors, including those …

Our skin contributes critically to health via its role as a barrier tissue, carefully regulating
passage of key substrates while also providing defense against exogenous threats …

Chronic itch is one of the most prominent clinical characteristics of diverse systematic
diseases. It is a devastating sensation in pathological diseases. Despite its importance …