The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges

GR Tundo, D Sbardella, AM Santoro, A Coletta… - Pharmacology & …, 2020 - Elsevier
Abstract Ubiquitin Proteasome System (UPS) is an adaptable and finely tuned system that
sustains proteostasis network under a large variety of physiopathological conditions. Its …

Preparing the ocular surface for glaucoma filtration surgery: An unmet clinical need

L Agnifili, M Sacchi, M Figus, C Posarelli… - Acta …, 2022 - Wiley Online Library
The mutual relationship among medical therapy, ocular surface (OS) and filtration surgery
(FS) represents one of the most crucial issues in glaucoma management. As the long‐term …

[HTML][HTML] Ocular findings among patients surviving COVID-19

ÍF Costa, LP Bonifácio, F Bellissimo-Rodrigues… - Scientific Reports, 2021 - nature.com
To describe the medium-term ophthalmological findings in patients recovering from COVID-
19. Patients recovered from the acute phase of COVID-19 underwent a complete …

Influence of goniotomy size on treatment safety and efficacy for primary open-angle glaucoma: a multicenter study

Y Zhang, P Yu, Y Zhang, K Sugihara, X Zhu… - American journal of …, 2023 - Elsevier
Purpose To compare the efficacy and safety of 120-, 240-, and 360-degree goniotomy (GT)
with or without phacoemulsification with intraocular lens implantation (PEI) for patients with …

Regional scleral thickness as a risk factor for central serous chorioretinopathy

RF Spaide, YL Fisher, WK Ngo, I Barbazetto - Retina, 2022 - journals.lww.com
Purpose: To evaluate regional sclera thicknesses as possible risk factors for central serous
chorioretinopathy (CSC). Methods: Patients with CSC and controls were evaluated with …

[HTML][HTML] Intraocular pressure rise linked to silicone oil in retinal surgery: a review

M Nicolai, N Lassandro, A Franceschi, A Rosati… - Vision, 2020 - mdpi.com
Silicone oil represents the main choice for intraocular tamponade in cases of complicated
retinal detachment surgery. The intraocular pressure of an eye filled with silicone oil could …

Six-month effective treatment of corneal graft rejection

T Meng, J Zheng, M Chen, Y Zhao, H Sudarjat… - Science …, 2023 - science.org
Topical corticosteroid eye drop is the mainstay for preventing and treating corneal graft
rejection. While the frequent topical corticosteroid use is associated with risk of intraocular …

[HTML][HTML] Reciprocal regulation between lncRNA ANRIL and p15 in steroid-induced glaucoma

P Wan, S Huang, Y Luo, C Deng, J Zhou, E Long… - Cells, 2022 - mdpi.com
Steroid-induced glaucoma (SIG) is the most common adverse steroid-related effect on the
eyes. SIG patients can suffer from trabecular meshwork (TM) dysfunction, intraocular …

The treatment of glaucoma using topical preservative-free agents: an evaluation of safety and tolerability

AG Konstas, A Labbé, A Katsanos… - Expert Opinion on …, 2021 - Taylor & Francis
ABSTRACT Introduction: Preservative-free (PF) medications represent a valuable treatment
strategy in the lifelong management of glaucoma. By removing preservative toxicity, PF …

[HTML][HTML] Outcomes of goniotomy with or without secondary intraocular lens implantation in pediatric glaucoma following cataract surgery: a prospective pilot study

Y Zhang, W Chen, TPH Lin, X Zhang… - The Asia-Pacific …, 2023 - journals.lww.com
Purpose: To report the outcomes of a 120-degree goniotomy (GT) with or without secondary
intraocular lens (IOL) implantation in glaucoma following cataract surgery (GFCS). Design …