Advances in the diagnosis and management of well-differentiated neuroendocrine neoplasms

J Hofland, G Kaltsas, WW de Herder - Endocrine Reviews, 2020 - academic.oup.com
Neuroendocrine neoplasms constitute a diverse group of tumors that derive from the
sensory and secretory neuroendocrine cells and predominantly arise within the pulmonary …

What is new in the 2019 World Health Organization (WHO) classification of tumors of the digestive system: review of selected updates on neuroendocrine neoplasms …

N Assarzadegan… - Archives of pathology & …, 2021 - meridian.allenpress.com
Context.—The 5th edition of the World Health Organization classification of digestive system
tumors discusses several advancements and developments in understanding the etiology …

Epidemiologic trends of and factors associated with overall survival for patients with gastroenteropancreatic neuroendocrine tumors in the United States

Z Xu, L Wang, S Dai, M Chen, F Li, J Sun… - JAMA network …, 2021 - jamanetwork.com
Importance Although the incidence and prevalence of gastroenteropancreatic
neuroendocrine tumors (GEP-NETs) have been thought to have increased during the past …

[HTML][HTML] An organoid biobank of neuroendocrine neoplasms enables genotype-phenotype mapping

K Kawasaki, K Toshimitsu, M Matano, M Fujita, M Fujii… - Cell, 2020 - cell.com
Gastroenteropancreatic (GEP) neuroendocrine neoplasm (NEN) that consists of
neuroendocrine tumor and neuroendocrine carcinoma (NEC) is a lethal but under …

Integrated profiling of human pancreatic cancer organoids reveals chromatin accessibility features associated with drug sensitivity

X Shi, Y Li, Q Yuan, S Tang, S Guo, Y Zhang… - Nature …, 2022 - nature.com
Chromatin accessibility plays an essential role in controlling cellular identity and the
therapeutic response of human cancers. However, the chromatin accessibility landscape …

A consensus-developed morphological re-evaluation of 196 high-grade gastroenteropancreatic neuroendocrine neoplasms and its clinical correlations

H Elvebakken, A Perren, JY Scoazec, LH Tang… - …, 2021 - karger.com
High-grade gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are classified
according to morphology as well-differentiated neuroendocrine tumours (NETs) G3 or poorly …

The new WHO classification of gastrointestinal neuroendocrine tumors and immunohistochemical expression of somatostatin receptor 2 and 5

O Popa, SM Taban, S Pantea… - Experimental and …, 2021 - spandidos-publications.com
Abstract The 2019 World Health Organization (WHO) classification of gastrointestinal tumors
defines well‑differentiated grade 3 neuroendocrine tumors, the mixed neuroendocrine‑non …

Update on epidemiology, diagnosis, and biomarkers in gastroenteropancreatic neuroendocrine neoplasms

D Takayanagi, H Cho, E Machida, A Kawamura… - Cancers, 2022 - mdpi.com
Simple Summary Neuroendocrine neoplasms are divided into two groups: well-
differentiated neuroendocrine tumors and poorly differentiated neuroendocrine carcinomas …

Emerging role of RNA methyltransferase METTL3 in gastrointestinal cancer

Q Wang, W Geng, H Guo, Z Wang, K Xu… - Journal of hematology & …, 2020 - Springer
Gastrointestinal cancer, the most common solid tumor, has a poor prognosis. With the
development of high-throughput sequencing and detection technology, recent studies have …

Neuroendocrine neoplasia of the gastrointestinal tract revisited: towards precision medicine

G Rindi, B Wiedenmann - Nature Reviews Endocrinology, 2020 - nature.com
Over the past 5 years, a number of notable research advances have been made in the field
of neuroendocrine cancer, specifically with regard to neuroendocrine cancer of the …