Abstract Gastro-entero-pancreatic (GEP-NET) and thoracic neuroendocrine tumours (NETs)
are one of the most heritable groups of neoplasms in the body, being multiple endocrine …

Most pancreatic neuroendocrine neoplasms (pNEN) occur sporadically but they can also
occur as part of multiple endocrine neoplasia type 1 (MEN1). MAX was originally described …

Context.—Pancreatic neuroendocrine neoplasms (PanNENs) represent a heterogeneous
group of epithelial tumors of the pancreas showing neuroendocrine differentiation. These …

Simple Summary Although ileal neuroendocrine tumors are the most common tumors of the
small intestine, they are not well-defined at the genetic level. Unlike most cancers, they have …

Few models exist for studying neuroendocrine tumors (NETs), and there are mounting
concerns that the currently available array of cell lines is not representative of NET biology …

High-throughput analysis, including next-generation sequencing and microarrays, have
strongly improved our understanding of cancer biology. However, genomic data on rare …

Introduction Reprogramming of cellular metabolism is now a hallmark of tumorigenesis. In
recent years, research on pancreatic neuroendocrine tumors (pNETs) has focused on …

Background The four major pathways in gastroenteropancreatic neuroendocrine neoplasms
(GEP-NENs) including chromatin remodeling, DNA damage repair, activation of mTOR …

Abstract Purpose of Review Classification and nomenclature of neuroendocrine neoplasms
(NEN) have frequently changed over the last years. These changes reflect both increasing …

Aims The aim of our study was to determine the effect of histone deacetylase (HDAC)
inhibitors (HDACis) on somatostatin type-2 receptor (SSTR2) expression and [111 In] In …