Complement has long been considered a key innate immune effector system that mediates
host defence and tissue homeostasis. Yet, growing evidence has illuminated a broader …

The complement system is recognised as a protector against blood-borne pathogens and a
controller of immune system and tissue homoeostasis. However, dysregulated complement …

Effective inhibition of the complement system is needed to prevent the accelerated
clearance of nanomaterials by complement cascade and inflammatory responses. Here we …

This study examined the effect of combining the sandblasting and anodising of titanium
alloys used in implants on the cell response and protein adsorption patterns. The titanium …

Most drugs that target the complement system are designed to inhibit the complement
pathway at either the proximal or terminal levels. The use of a natural complement regulator …

Infections are one of the most significant healthcare and economic burdens across the world
as underscored by the recent coronavirus pandemic. Moreover, with the increasing …

Surface modification with heparin is a powerful biomaterial coating strategy that protects
against innate immunity activation since heparin is a part of the proteoglycan heparan …