[HTML][HTML] Clinical significance of oxidative stress markers as angioinvasion and metastasis indicators in papillary thyroid cancer

A Buczyńska, I Sidorkiewicz, M Kościuszko… - Scientific Reports, 2023 - nature.com
Angioinvasion remains the important prognostic feature in papillary thyroid cancer (PTC)
patients. Literature data indicates several markers that may be associated with oxidative …

[HTML][HTML] Hypoxic Conditions Modulate Chondrogenesis through the Circadian Clock: The Role of Hypoxia-Inducible Factor-1α

KZ Juhász, T Hajdú, P Kovács, J Vágó, C Matta… - Cells, 2024 - mdpi.com
Hypoxia-inducible factor-1 (HIF-1) is a heterodimer transcription factor composed of an
alpha and a beta subunit. HIF-1α is a master regulator of cellular response to hypoxia by …

The role of tumor‐associated macrophages in hepatocellular carcinoma progression: A narrative review

X Zhang, C Yu, S Zhao, M Wang, L Shang… - Cancer …, 2023 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in the world,
with complex etiology and mechanism, and a high mortality rate. Tumor‐associated …

GSH-Responsive Polymeric Micelles for Remodeling the Tumor Microenvironment to Improve Chemotherapy and Inhibit Metastasis in Breast Cancer

Y Zeng, G Song, S Zhang, S Li, T Meng… - …, 2023 - ACS Publications
The tumor microenvironment (TME) of breast cancer is hypoxic, which can promote tumor
progression, including invasion and metastasis, and limit the efficacy of anti-tumor treatment …

WDR72 Enhances the Stemness of Lung Cancer Cells by Activating the AKT/HIF‐1α Signaling Pathway

X Ouyang, X Shi, N Huang, Y Yang, W Zhao… - Journal of …, 2022 - Wiley Online Library
Objectives. Lung cancer is a common malignant tumor with high morbidity and mortality rate.
Lung cancer stem cells are crucial in the development of lung cancer. In this study, we …

[HTML][HTML] PRMT5 Mediated HIF1α Signaling and Ras-Related Nuclear Protein as Promising Biomarker in Hepatocellular Carcinoma

W Abumustafa, D Castven, FS Sharif-Askari… - Biology, 2024 - mdpi.com
Simple Summary The protein arginine N-methyltransferase 5 (PRMT5) has been identified
as a promising therapeutic target in various cancers. However, its role in hepatocellular …

Transmembrane protein 147, as a potential Sorafenib target, could expedite cell cycle process and confer adverse prognosis in hepatocellular carcinoma

W Ma, X Zhang, J Lu, S Lv, Z Zhang… - Molecular …, 2023 - Wiley Online Library
TMEM147 was identified as a core component of ribosome‐bound translocon complex at
ER/NE. So far, sparse studies reported its expression profiling and oncological implications …

[HTML][HTML] Activation of RhoA/ROCK2 signaling by hypoxia-inducible factor 1α in promoting tumor growth and metastasis in human colon cancer

K Du, P Wang, J Liu, J Ren, G Zheng… - Journal of …, 2024 - jgo.amegroups.org
Background: Recent evidence strongly suggests the profound role of the tumor
microenvironment in cancer development and progression. A hypoxic microenvironment is …

[HTML][HTML] Intravoxel incoherent motion imaging used to assess tumor microvascular changes after transarterial chemoembolization in a rabbit VX2 liver tumor model

Z Cheng, H Qin, W Cao, H He, S Zhang, Y Yang… - Frontiers in …, 2023 - frontiersin.org
Purpose: to evaluate the correlation between microvascular density (MVD) and intravoxel
incoherent motion (IVIM) magnetic resonance imaging (MRI) parameters and the effect of …

[HTML][HTML] Study of the role of neuropilin-1 in the development, prognosis and cellular response to lenvatinib in human hepatocellular carcinoma

PF Palanca - 2023 - dialnet.unirioja.es
Hepatocellular carcinoma (HCC), the main type of primary liver cancer, constitutes the sixth
most common and third most deadly cancer worldwide, respectively. Due to the late …