Parkinson's disease is a neurodegenerative disorder whose cardinal manifestations are due
primarily to a profound deficit in brain dopamine. Since the 1980s, several therapeutic …

Mainly known for its more famous parent compound, ethanol, acetaldehyde was first studied
in the 1940s, but then research interest in this compound waned. However, in the last two …

Abstract Salsolinol (1-methyl-6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline) is a
tetrahydroisoquinoline derivative whose presence in humans was first detected in the urine …

After decades of uncertainties and drawbacks, the study on the role and significance of
acetaldehyde in the effects of ethanol seemed to have found its main paths. Accordingly, the …

Pinocembrin (PB), the most abundant flavonoid in propolis, has been proven to have
neuroprotective property against neurotoxicity in vivo and in vitro. Our recent study …

Parkinson's disease involves the progressive degeneration of dopaminergic neurons in the
substantia nigra. However, the etiology of the disease remains to be elucidated …

The effect of single and multiple 1‐methyl‐1, 2, 3, 4‐tetrahydroisoquinoline (1MeTIQ) and 1‐
benzyl‐1, 2, 3, 4‐tetrahydroisoquinoline (1BnTIQ) administration on concentrations of …

Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridinium
cation (MPP+) are selective dopaminergic neurotoxins producing Parkinsonism. MPTP is …

Mitochondrial toxin involved in neurodegeneration 3. Toxin that produced a
neurodegeneration like that found in parkinson's disease 3.1. 1. Methyl-4-phenyl-1, 2, 3, 6 …

The possible involvement of salsolinol (Sal), an endogenous condensation product of ACD
(the first metabolite of ethanol) and dopamine, in the neurochemical basis underlying …