Intrinsic, widefield optical imaging of hemodynamics in rodent models of Alzheimer's disease and neurological injury

C Crouzet, T Phan, RH Wilson, TJ Shin… - …, 2023 - spiedigitallibrary.org
The complex cerebrovascular network is critical to controlling local cerebral blood flow
(CBF) and maintaining brain homeostasis. Alzheimer's disease (AD) and neurological injury …

[HTML][HTML] Two-photon microscopy: application advantages and latest progress for in vivo imaging of neurons and blood vessels after ischemic stroke

J Li, X Wu, Y Fu, H Nie, Z Tang - Reviews in the Neurosciences, 2023 - degruyter.com
Two-photon microscopy (TPM) plays an important role in the study of the changes of the two
important components of neurovascular units (NVU)–neurons and blood vessels after …

Aerobic exercise reverses aging-induced depth-dependent decline in cerebral microcirculation

P Shin, Q Pian, H Ishikawa, G Hamanaka… - Elife, 2023 - elifesciences.org
Aging is a major risk factor for cognitive impairment. Aerobic exercise benefits brain function
and may promote cognitive health in older adults. However, underlying biological …

[HTML][HTML] The effects of time restricted feeding on age-related changes in the mouse retina

CA Huston, M Milan, ML Vance, MA Bickel… - Experimental …, 2024 - Elsevier
Dietary modifications such as caloric restriction (CR) and intermittent fasting (IF) have
gained popularity due to their proven health benefits in aged populations. In time restricted …

[HTML][HTML] Roles of mechanosensitive ion channel PIEZO1 in the pathogenesis of brain injury after experimental intracerebral hemorrhage

M Qi, R Liu, F Zhang, Z Yao, M Zhou, X Jiang, S Ling - Neuropharmacology, 2024 - Elsevier
Secondary brain injury after intracerebral hemorrhage (ICH) is the main cause of poor
prognosis in ICH patients, but the underlying mechanisms remain less known. The …

Cerebrovascular function in aging

AE Walker, AE Cullen, BG Fico, JN Barnes - Cardiovascular …, 2023 - Springer
As our population continues to age, the importance of understanding age-related diseases
(eg, cerebrovascular disease, Alzheimer's disease) and dysfunction becomes an increasing …

Capillary responses to functional and pathological activations rely on the capillary states at rest

H Suzuki, H Takeda, H Takuwa, B Ji… - Journal of Cerebral …, 2023 - journals.sagepub.com
Brain capillaries play a crucial role in maintaining cellular viability and thus preventing
neurodegeneration. The aim of this study was to characterize the brain capillary morphology …

Intrinsic, widefield optical imaging of hemodynamics in rodent models of Alzheimer's disease and neurological injury

TJ Shin, B Choi - 2023 - spiedigitallibrary.org
The complex cerebrovascular network is critical to controlling local cerebral blood flow
(CBF) and maintaining brain homeostasis. Alzheimer's disease (AD) and neurological injury …

Finding Signal in the Noise: High-Fidelity, Quantitative, Optical Blood Perfusion Imaging with Interference

AM Safi - 2022 - search.proquest.com
For label-free, non-invasive, wide field-of-view (FOV) imaging/monitoring of blood flow,
speckle-based approaches are gaining popularity. However, to obtain quantitative flow …