This review describes the role of CXCL1, a chemokine crucial in inflammation as a
chemoattractant for neutrophils, in physiology and in selected major non-cancer diseases …

Methicillin‐resistant Staphylococcus aureus (MRSA)‐infected skin wounds have caused a
variety of diseases and seriously endanger global public health. Therefore …

Glial cells have been proposed as a source of neural progenitors, but the mechanisms
underpinning the neurogenic potential of adult glia are not known. Using single cell …

Piezo1, a non-selective cation channel directly activated by mechanical forces, is widely
expressed in the digestive system and participates in biological functions physiologically …

Background Mesenchymal stem cell (MSC) treatment plays a major role in the management
of acute lung injury (ALI), and neutrophils are the initial line of defense against ALI …

Background The upregulated expression of CXCL1 has been validated in colorectal cancer
patients. As a potential biotherapeutic target for colorectal cancer, the mechanism by which …

Background Coronary heart disease (CHD) is the leading cause of death in the world.
Unfortunately, many of the key diagnostic tools for CHD are insensitive, invasive, and costly; …

VEGF inhibitors are one of the most successful antiangiogenic drugs in the treatment of
many solid tumors. Nevertheless, pancreatic adenocarcinoma (PAAD) cells can reinstate …

The TGFβ receptor inhibitor galunisertib demonstrated efficacy in patients with pancreatic
ductal adenocarcinoma (PDAC) in the randomized phase II H9H-MC-JBAJ study, which …

Background Alterations in several tripartite motif-containing (TRIM) family proteins have
been implicated in the pathogenesis of lung cancer. TRIM28, a member of the TRIM E3 …