De novo assembly, annotation, and comparative analysis of 26 diverse maize genomes

MB Hufford, AS Seetharam, MR Woodhouse… - Science, 2021 - science.org
We report de novo genome assemblies, transcriptomes, annotations, and methylomes for
the 26 inbreds that serve as the founders for the maize nested association mapping …

An improved assembly and annotation of the allohexaploid wheat genome identifies complete families of agronomic genes and provides genomic evidence for …

BJ Clavijo, L Venturini, C Schudoma… - Genome …, 2017 - genome.cshlp.org
Advances in genome sequencing and assembly technologies are generating many high-
quality genome sequences, but assemblies of large, repeat-rich polyploid genomes, such as …

Study of tofacitinib in refractory dermatomyositis: an open‐label pilot study of ten patients

JJ Paik, L Casciola‐Rosen, JY Shin… - Arthritis & …, 2021 - Wiley Online Library
Objective This open‐label 12‐week study was conducted to evaluate the efficacy and safety
of tofacitinib, a JAK inhibitor, in treatment‐refractory active dermatomyositis (DM). Methods …

Stout camphor tree genome fills gaps in understanding of flowering plant genome evolution

SM Chaw, YC Liu, YW Wu, HY Wang, CYI Lin, CS Wu… - Nature plants, 2019 - nature.com
We present reference-quality genome assembly and annotation for the stout camphor tree
(Cinnamomum kanehirae (Laurales, Lauraceae)), the first sequenced member of the …

[HTML][HTML] Non-coding natural antisense transcripts: Analysis and application

JC Krappinger, L Bonstingl, K Pansy, K Sallinger… - Journal of …, 2021 - Elsevier
Non-coding natural antisense transcripts (ncNATs) are regulatory RNA sequences that are
transcribed in the opposite direction to protein-coding or non-coding transcripts. These …

Gapless assembly of maize chromosomes using long-read technologies

J Liu, AS Seetharam, K Chougule, S Ou… - Genome Biology, 2020 - Springer
Creating gapless telomere-to-telomere assemblies of complex genomes is one of the
ultimate challenges in genomics. We use two independent assemblies and an optical map …

[PDF][PDF] Leveraging multiple transcriptome assembly methods for improved gene structure annotation

L Venturini, S Caim, GG Kaithakottil, DL Mapleson… - …, 2018 - academic.oup.com
Background The performance of RNA sequencing (RNA-seq) aligners and assemblers
varies greatly across different organisms and experiments, and often the optimal approach is …

ZCCHC8, the nuclear exosome targeting component, is mutated in familial pulmonary fibrosis and is required for telomerase RNA maturation

DL Gable, V Gaysinskaya, CC Atik… - Genes & …, 2019 - genesdev.cshlp.org
Short telomere syndromes manifest as familial idiopathic pulmonary fibrosis; they are the
most common premature aging disorders. We used genome-wide linkage to identify …

[HTML][HTML] Long noncoding RNA study: Genome-wide approaches

S Tao, Y Hou, L Diao, Y Hu, W Xu, S Xie, Z Xiao - Genes & diseases, 2023 - Elsevier
Long noncoding RNAs (lncRNAs) have been confirmed to play a crucial role in various
biological processes across several species. Though many efforts have been devoted to the …

Single-nucleus RNA-seq reveals that MBD5, MBD6, and SILENZIO maintain silencing in the vegetative cell of developing pollen

L Ichino, CL Picard, J Yun, M Chotai, S Wang, EK Lin… - Cell reports, 2022 - cell.com
Silencing of transposable elements (TEs) drives the evolution of numerous redundant
mechanisms of transcriptional regulation. Arabidopsis MBD5, MBD6, and SILENZIO act as …