Does the polypill improve patient adherence compared to its individual formulations? A systematic review

A Baumgartner, K Drame, S Geutjens, M Airaksinen - Pharmaceutics, 2020 - mdpi.com
Many patients, especially those with a high pill burden and multiple chronic illnesses, are
less adherent to medication. In medication treatments utilizing polypills, this problem might …

[图书][B] Guideline for the pharmacological treatment of hypertension in adults

World Health Organization - 2021 - books.google.com
In this guideline, the World Health Organization (WHO) provides the most current and
relevant evidence-based global public health guidance on the initiation of treatment with …

Antihypertensive combination treatment: state of the art

M Burnier - Current hypertension reports, 2015 - Springer
An adequate control of blood pressure is essential to reduce the risk of target organ
damages and cardiovascular events in patients with hypertension. Yet, it is well recognized …

Fixed-dose combination antihypertensive medications, adherence, and clinical outcomes: a population-based retrospective cohort study

AA Verma, W Khuu, M Tadrous, T Gomes… - PLoS …, 2018 - journals.plos.org
Background The majority of people with hypertension require more than one medication to
achieve blood pressure control. Many patients are prescribed multipill antihypertensive …

[HTML][HTML] Fixed‐dose combination pharmacologic therapy to improve hypertension control worldwide: clinical perspective and policy implications

DJ DiPette, J Skeete, E Ridley… - The Journal of …, 2019 - ncbi.nlm.nih.gov
Despite significant advances in health care over the last 50 years, the global cardiovascular
disease burden continues to increase with dire im‐plications. It is well known that …

[HTML][HTML] Impact of single-pill combination therapy on adherence, blood pressure control, and clinical outcomes: a rapid evidence assessment of recent literature

K Tsioufis, R Kreutz, G Sykara, J van Vugt… - Journal of …, 2020 - journals.lww.com
Objective: The 2018 European Society of Cardiology/European Society of Hypertension
Guidelines for the management of arterial hypertension raised the need for evidence to …

Are two drugs better than one? A review of combination therapies for hypertension

Y Rochlani, MH Khan, M Banach… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Current guidelines for pharmacotherapy briefly describe a role for combination
antihypertensive therapy. However, guidance on whether combination therapy should be …

Comparison of therapy persistence for fixed versus free combination antihypertensives: a retrospective cohort study

T Grimmsmann, W Himmel - BMJ open, 2016 - bmjopen.bmj.com
Objectives The aim of the study was to compare therapy persistence among patients who
started with one of three drug regimens: a monotherapy, or combination therapy either as a …

Fixed-dose triple-combination treatments in the management of hypertension.

CV Ram - Managed Care (Langhorne, Pa.), 2013 - europepmc.org
Hypertension remains uncontrolled in approximately 50% of patients with hypertension,
which increases the risk of cardiovascular morbidity and mortality in these individuals. A key …

How does prescribing for antihypertensive products stack up against guideline recommendations? An Australian population‐based study (2006–2014)

AL Schaffer, SA Pearson… - British Journal of Clinical …, 2016 - Wiley Online Library
Aims We describe choice of first‐line antihypertensive drug therapy and uptake of fixed‐
dose combinations (FDCs) in Australia, and investigate the impact of initiation on FDCs and …