Sestrins (Sesns), highly conserved stress-inducible metabolic proteins, are known to protect
organisms against various noxious stimuli including DNA damage, oxidative stress …

Cardiovascular disease (CVD) has become a severe threat to human beings with increasing
morbidity and mortality. Isorhamnetin (Iso) shows multiple bioactivities, especially in the …

Forkhead box, class O (FOXO) family proteins are widely expressed and highly conserved
transcriptional regulators that modulate cellular fuel metabolism, stress resistance and cell …

Abstract Background Sestrin2 (SESN2), a stress-inducible protein, has been reported to
protect against denervated muscle atrophy through unfolded protein response and …

The review presents current concepts of the molecular mechanisms of oxidative stress
development and describes main stages of the free-radical reactions in oxidative stress …

Objective: This study aimed to elucidate the pharmacological effects of sesamin (Ses) and its
mechanism of action towards PM2. 5-induced cardiovascular injuries. Method: Forty …

Glomerular mesangial cell proliferation and extracellular matrix accumulation contribute to
the progression of diabetic nephropathy (DN). As a conserved stress-inducible protein …

Obesity is of concern to the population because it is known to cause inflammation and
oxidative stress throughout the body, leading to patient predisposition for health conditions …

Sestrin2 is a highly conserved protein that can be induced under a variety of stress
conditions, including DNA damage, oxidative stress, endoplasmic reticulum (ER) stress, and …

The present study was to explore whether alarin could alleviate heart failure (HF) and
attenuate cardia fibrosis via inhibiting oxidative stress. The fibrosis of cardiac fibroblasts …