[HTML][HTML] M. tuberculosis Transcription Machinery: A Review on the Mycobacterial RNA Polymerase and Drug Discovery Efforts

F Stephanie, USF Tambunan, TJ Siahaan - Life, 2022 - mdpi.com
Mycobacterium tuberculosis (MTB) is the main source of tuberculosis (TB), one of the oldest
known diseases in the human population. Despite the drug discovery efforts of past …

Disulfiram and copper ions kill Mycobacterium tuberculosis in a synergistic manner

AG Dalecki, M Haeili, S Shah, A Speer… - Antimicrobial agents …, 2015 - Am Soc Microbiol
Tuberculosis is a severe disease affecting millions worldwide. Unfortunately, treatment
strategies are hampered both by the prohibitively long treatment regimen and the rise of …

Surface hydrolysis of sphingomyelin by the outer membrane protein Rv0888 supports replication of Mycobacterium tuberculosis in macrophages

A Speer, J Sun, O Danilchanka, V Meikle… - Molecular …, 2015 - Wiley Online Library
Sphingomyelinases secreted by pathogenic bacteria play important roles in host–pathogen
interactions ranging from interfering with phagocytosis and oxidative burst to iron …

[图书][B] In singulo study of the transcription elongation by Mycobacterium tuberculosis RNA polymerase and its inhibition by Aroyl-Aryl-Phenylalaninamide …

OCH Asmat - 2022 - search.proquest.com
Tuberculosis (TB) is an airborne disease that kills 1.5 million people and affects~ 9 million
worldwide. Its etiological agent, Mycobacterium tuberculosis (Mtb), persists in a third of the …

[PDF][PDF] Studies Towards the Total Synthesis of the Antibiotic Bu-2313 B and a Bu-2313–Streptolydigin Hybrid

C Bomio-Confaglia - 2016 - research-collection.ethz.ch
Abstract Bu-2313 A/B (I/II) are highly potent, broad spectrum antibiotics which are produced
by the oligosporic actinomycete strain No. E864-61 (Figure 1). Their isolation, structure and …