[HTML][HTML] Potential application of sucrose acetate isobutyrate, and glyceryl monooleate for nanonization and bioavailability enhancement of rivaroxaban tablets

AA Al-Shoubki, MH Teaima, R Abdelmonem… - Pharmaceutical Science …, 2024 - Elsevier
This study aimed to investigate the use of Sucrose acetate isobutyrate (SAIB) and Glyceryl
monooleate (GMO) as co-formers for creating Cubosomes and SAIB-based nanodispersions …

Sucrose acetate isobutyrate (SAIB) and glyceryl monooleate (GMO) hybrid nanoparticles for bioavailability enhancement of rivaroxaban: an optimization study

AA Al-Shoubki, MH Teaima… - Pharmaceutical …, 2023 - Taylor & Francis
This study aims to improve the RXB bioavailability using hybrid nanoparticles. A modified
melt dispersion technique created different formulas with varying GMO-SAIB: RXB and GMO …

Novel rivaroxaban-loaded microsphere systems with different surface microstructure for enhanced oral bioavailability

MJ Choi, MR Woo, K Baek, JS Kim, JO Kim… - Drug Delivery and …, 2024 - Springer
This study compares rivaroxaban-loaded polymeric microsphere systems with three types of
surface microstructure. Three types of polymeric microspheres loaded with rivaroxaban were …

Quality-by-design-based development of Rivaroxaban-Loaded Liquisolid Compact tablets with Improved Biopharmaceutical attributes

P Shah, H Desai, B Vyas, M Lalan, M Kulkarni - AAPS PharmSciTech, 2023 - Springer
Rivaroxaban (RXN) finds use in the management of pulmonary embolism and deep vein
thrombosis. Its poor solubility (5–7 µg/mL) and P-gp-mediated efflux from intestinal lining …

[PDF][PDF] Ameliorating the Poor Dissolution Rate of Selexipag in Aqueous Acidic Conditions Following Confinement into Mesoporous Silica

MS Attia, FES Ghazy - Ind. J. Pharm. Edu. Res, 2023 - researchgate.net
ABSTRACT Background: Pulmonary Arterial Hypertension (PAH) is a serious condition with
available treatment options, including Selexipag (SXP), a selective prostacyclin receptor …

[PDF][PDF] BIOAVAILABILITY ENHANCEMENT STRATEGIES FOR RIVAROXABAN: A NOTEWORTHY REVIEW

AA AL-SHOUBKI, MH TEAIMA, R ABDELMONEM… - Int J App …, 2023 - researchgate.net
This review article discusses Rivaroxaban (RXB), an anticoagulant that has gained much
attention due to its ability to prevent blood clots from forming in the body. However, one of …

[PDF][PDF] Pharmaceutical Science Advances

AA Al-Shoubki, MH Teaima, R Abdelmonem… - researchgate.net
This study aimed to investigate the use of Sucrose acetate isobutyrate (SAIB) and Glyceryl
monooleate (GMO) as co-formers for creating Cubosomes and SAIB-based nanodispersions …