Scalar translocation comparison between lateral wall and perimodiolar cochlear implant arrays‐a meta‐analysis

S Jwair, A Prins, I Wegner, RJ Stokroos… - The …, 2021 - Wiley Online Library
Objectives/Hypothesis Two types of electrode arrays for cochlear implants (CIs) are
distinguished: lateral wall and perimodiolar. Scalar translocation of the array can lead to …

Intracochlear fibrosis and the foreign body response to cochlear implant biomaterials

MJ Foggia, RV Quevedo… - Laryngoscope …, 2019 - Wiley Online Library
Objective To report current knowledge on the topic of intracochlear fibrosis and the foreign
body response following cochlear implantation (CI). Methods A literature search was …

First‐in‐human intracochlear application of human stromal cell‐derived extracellular vesicles

A Warnecke, N Prenzler, J Harre, U Köhl… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) derived from the secretome of human mesenchymal stromal
cells (MSC) contain numerous factors that are known to exert anti‐inflammatory effects. MSC …

Zwitterionic polymer/polydopamine coating of electrode arrays reduces fibrosis and residual hearing loss after cochlear implantation

A Chen, D Chen, K Lv, G Li, J Pan, D Ma… - Advanced …, 2023 - Wiley Online Library
Since the first surgery 50 years ago, cochlear implantation (CI) is the major treatment for
patients with severe sensorineural hearing loss. However, unexpected foreign body …

Antifouling photograftable zwitterionic coatings on PDMS substrates

BL Leigh, E Cheng, L Xu, A Derk, MR Hansen… - Langmuir, 2018 - ACS Publications
The foreign body response (FBR) to implantable materials can negatively impact
performance of medical devices such as the cochlear implant. Engineering surfaces that …

Electrocochleography and cognition are important predictors of speech perception outcomes in noise for cochlear implant recipients

A Walia, MA Shew, D Kallogjeri, CC Wick… - Scientific reports, 2022 - nature.com
Although significant progress has been made in understanding outcomes following cochlear
implantation, predicting performance remains a challenge. Duration of hearing loss, age at …

Macrophages in the human cochlea: saviors or predators—a study using super-resolution immunohistochemistry

W Liu, M Molnar, C Garnham, H Benav… - Frontiers in …, 2018 - frontiersin.org
The human inner ear, which is segregated by a blood/labyrinth barrier, contains resident
macrophages [CD163, ionized calcium-binding adaptor molecule 1 (IBA1)-, and CD68 …

Advances in hearing preservation in cochlear implant surgery

O Tarabichi, M Jensen, MR Hansen - Current opinion in …, 2021 - journals.lww.com
Hearing preservation is possible using soft surgical techniques and electrode arrays
designed to minimize cochlear trauma; however, a subset of patients suffer from partial to …

Predictive factors for short‐and long‐term hearing preservation in cochlear implantation with conventional‐length electrodes

GB Wanna, BP O'Connell, DO Francis… - The …, 2018 - Wiley Online Library
Objectives/Hypothesis The aims of this study were to investigate short‐and long‐term rates
of hearing preservation after cochlear implantation and identify factors that impact hearing …

Potential insertion complications with cochlear implant electrodes

A Ishiyama, F Risi, P Boyd - Cochlear Implants International, 2020 - Taylor & Francis
Objectives: The aim of this discussion paper and literature review was to estimate the
incidence of a variety of complications associated with the surgical placement of cochlear …