The ongoing COVID-19 pandemic has imposed a series of challenges on the scientific
community. One of the biggest was the development of safe and effective vaccines in record …

Background China has been using inactivated coronavirus disease 2019 (COVID-19)
vaccines as primary series and booster doses to protect the population from severe to fatal …

Introduction The SARS-CoV-2 Omicron variant has become the dominant SARS-CoV-2
variant and exhibits immune escape to current COVID-19 vaccines, the further boosting …

We sought to assess breakthrough SARS-CoV-2 infections in vaccinated individuals by
variant distribution and to identify the common risk associations. The PubMed, Web of …

Background Over a dozen vaccines are in or have completed phase III trials at an
unprecedented speed since the World Health Organization (WHO) declared COVID-19 a …

Accurate determination of the concentration and viability of the viral vaccine vectors is
urgently needed for preventing the spread of the viral infections, but also supporting the …

Humanity did surprisingly well so far, considering how unprepared it was to respond to the
coronavirus disease 2019 (COVID-19) threat. By blending old and ingenious new …

Classic chimeric hemagglutinin (cHA) was designed to induce immune responses against
the conserved stalk domain of HA. However, it is unclear whether combining more than one …

Vaccination is an effective measure to prevent infectious diseases. Protective immunity is
induced when the immune system is exposed to a vaccine formulation with appropriate …

The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic has led to
an unprecedented public health crisis. The collective global response has led to production …