The role of immunosuppressive myofibroblasts in the aging process and age-related diseases
A Salminen - Journal of Molecular Medicine, 2023 - Springer
Tissue-resident fibroblasts are mesenchymal cells which control the structural integrity of the
extracellular matrix (ECM). Fibroblasts possess a remarkable plasticity to allow them to …
extracellular matrix (ECM). Fibroblasts possess a remarkable plasticity to allow them to …
Advances in immunotherapy for gynecological Malignancies
M Tu, J Xu - Critical reviews in oncology/hematology, 2023 - Elsevier
To date, surgery, chemotherapy and radiotherapy are mainly used to treat or remove
gynecological malignancies. However, these approaches have their limitations when facing …
gynecological malignancies. However, these approaches have their limitations when facing …
Immune and non-immune inflammatory cells involved in autoimmune fibrosis: new discoveries
Fibrosis is an important health problem and its pathogenetic activation is still largely
unknown. It can develop either spontaneously or, more frequently, as a consequence of …
unknown. It can develop either spontaneously or, more frequently, as a consequence of …
Advances in the role and mechanism of fibroblasts in fracture healing
H Wang, L Qi, C Shema, K Jiang, P Ren… - Frontiers in …, 2024 - frontiersin.org
With the development of social population ageing, bone fracture has become a global public
health problem due to its high morbidity, disability and mortality. Fracture healing is a …
health problem due to its high morbidity, disability and mortality. Fracture healing is a …
Immune response to IL6 gradient in a diffusion-based microfluidic labchip
P Sardarabadi, KY Lee, WL Sun, CH Liu - Sensors and Actuators B …, 2024 - Elsevier
Cell migration plays a crucial role in uncovering many physiological phenomena and
predicting several pathologies, such as immune cell trafficking, tissue-specific …
predicting several pathologies, such as immune cell trafficking, tissue-specific …
Combination of Anti-Angiogenics and Immunotherapies in Renal Cell Carcinoma Show Their Limits: Targeting Fibrosis to Break through the Glass Ceiling?
M Teisseire, S Giuliano, G Pagès - Biomedicines, 2024 - mdpi.com
[HTML][HTML] Interactions between cancer-associated fibroblasts and T-cells: functional crosstalk with targeting and biomarker potential
V Milosevic, A Östman - Upsala Journal of Medical Sciences, 2024 - ncbi.nlm.nih.gov
Cancer-associated fibroblasts (CAFs) are a heterogeneous cell population recognized as a
key component of the tumour microenvironment (TME). Cancer-associated fibroblasts are …
key component of the tumour microenvironment (TME). Cancer-associated fibroblasts are …
Inflammatory tissue priming: novel insights and therapeutic opportunities for inflammatory rheumatic diseases
MH Hoffmann, H Kirchner, G Krönke… - Annals of the …, 2024 - ard.bmj.com
Due to optimised treatment strategies and the availability of new therapies during the last
decades, formerly devastating chronic inflammatory diseases such as rheumatoid arthritis or …
decades, formerly devastating chronic inflammatory diseases such as rheumatoid arthritis or …
[PDF][PDF] Single-Cell Characterization of Cellular Networks in T Cell-Mediated Skin Inflammation
L Erlmeier, MAN Fortelny, APDI Gratz - eplus.uni-salzburg.at
Our study aimed to investigate the role of HDAC1 or HDAC2 in a model of T cell-mediated
skin inflammation. Specifically, we adoptively transferred OTII CD4+ T cells obtained from …
skin inflammation. Specifically, we adoptively transferred OTII CD4+ T cells obtained from …