Bioengineering: A Promising Approach for Standardization and Automation of ART

F Amjad, MA Hajari, A Dalman, H Baharvand… - F&S Reviews, 2024 - Elsevier
Assisted reproductive technology (ART) is a commonly used treatment for infertile couples.
However, the suboptimal success rate of ART highlights the urgent need for optimization …

[HTML][HTML] Viscoelastic properties of zona pellucida of oocytes characterized by transient electrical impedance spectroscopy

D Azarkh, Y Cao, J Floehr, U Schnakenberg - Biosensors, 2023 - mdpi.com
The success rate in vitro fertilization is significantly linked to the quality of the oocytes. The
oocyte's membrane is encapsulated by a shell of gelatinous extracellular matrix, called zona …

Electrical sensing of single oocytes in microfluidic systems: A mini review

U Schnakenberg, Y Cao - Applied Research, 2024 - Wiley Online Library
The noninvasive and label‐free electrical characterization of single cells is increasingly
gaining interest over the last years. Besides cancer cells, oocytes are in the focus of those …

Balancing of Flow at Microfluidic Apertures

Y Cao, E Yilmaz, U Schnakenberg - physica status solidi (a), 2023 - Wiley Online Library
Computational fluid dynamics simulations are used to obtain a radially symmetrical flow
profile at an aperture of a microfluidic channel by manually arranging flow‐directing …

Characterization of oocyte hardening using a microfluidic aspiration-assisted electrical impedance spectroscopy system

Y Cao, J Floehr, U Schnakenberg - 2023 IEEE 36th …, 2023 - ieeexplore.ieee.org
This paper reports a microfluidic aspiration-assisted electrical impedance spectroscopy
system (MAEIS) with the aim of characterizing oocyte hardening for in-vitro fertilization (IVF) …

Microfluidic System for Recording Fast Ion Channel Kinetics with Electrical Impedance Spectroscopy

Y Cao, L Cheng, O Liborio, R Hausmann… - 2023 IEEE …, 2023 - ieeexplore.ieee.org
Ligand-gated ion channels (LGICs) are involved in many pathophysiological processes and
represent a relevant target for drug discovery. In this work, we developed a novel setup …

Elektrische Charakterisierung von Eizellen mit mikrofluidischen Systemen

U Schnakenberg, Y Cao - BIOspektrum, 2024 - Springer
Zusammenfassung Mithilfe der Technologien der Mikrosystemtechnik können Lab-on-a-
Chip-Systeme für Applikationen im Bereich der Biologie, Biochemie und Biotechnologie …