Polysaccharides from Phellinus linteus: A systematic review of their extractions, purifications, structures and functions

D Qin, S Han, M Liu, T Guo, Z Hu, Y Zhou… - International Journal of …, 2023 - Elsevier
Phellinus linteus (P. linteus) is a famous Chinese medicine and has a long history in China.
In recent years, P. linteus polysaccharides (PLPs) have attracted extensive attention …

[HTML][HTML] Dietary phytochemical and metabolic disease prevention: Focus on plant proteins

S Yang, G Tao, L Yang, X Wu, J Liu, F Dagher… - Frontiers in …, 2023 - frontiersin.org
Plant-based functional foods have attracted increasing research interest to validate their use
in preventing metabolic disease. Since it is increasingly recognized that inflammation …

[HTML][HTML] Baicalin ameliorates insulin resistance and regulates hepatic glucose metabolism via activating insulin signaling pathway in obese pre-diabetic mice

L Miao, X Zhang, H Zhang, MS Cheong, X Chen… - Phytomedicine, 2024 - Elsevier
Background Diabetes belongs to the most prevalent metabolic diseases worldwide, which is
featured with insulin resistance, closely associated with obesity and urgently needs to be …

[HTML][HTML] Anti-diabetic potential of apigenin, luteolin, and baicalein via partially activating PI3K/Akt/Glut-4 signaling pathways in insulin-resistant HepG2 cells

L Miao, H Zhang, MS Cheong, R Zhong… - Food Science and …, 2023 - Elsevier
Dietary flavonoids are abundant in natural plants and possess multiple pharmacological and
nutritional activities. In this study, apigenin, luteolin, and baicalein were chosen to evaluate …

Inhibitory mechanism of prenylated flavonoids isolated from mulberry leaves on α-glucosidase by multi-spectroscopy and molecular dynamics simulation

JL Tian, M Zhao, JY Xu, TM Lv, XC Liu… - Journal of Agricultural …, 2023 - ACS Publications
Flavonoids have always been considered as the chemical basis for the hypoglycemic effect
of mulberry leaves. In the course of our search for hypoglycemic effect agents from natural …

Systemic pharmacology reveal the mechanism by which the Qiangjin Zhuanggu Qufeng mixture inhibits LPS-induced pyroptosis of rat nucleus pulposus cells

D Wang, L Zhang, D He, Y Zhang, J Bao, W Gao… - Phytomedicine, 2023 - Elsevier
Objective Low back pain (LBP) is a worldwide health issue primarily attributed to
intervertebral disc degeneration (IVDD). Qiangjin Zhuang Qufeng mixture (QJZG), an …

[HTML][HTML] Citri Reticulatae Pericarpium (Chenpi) Protects against Endothelial Dysfunction and Vascular Inflammation in Diabetic Rats

Y Wang, X Zhang, C Zhou, H Khan, M Fu, WS Cheang - Nutrients, 2022 - mdpi.com
Dried tangerine peel (Citri reticulatae Pericarpium, CRP; Chenpi in Chinese) possesses
medicine and food homology with hypolipidemic, anti-inflammatory and antioxidant …

Macrophage-derived exosomes as advanced therapeutics for inflammation: current progress and future perspectives

Y Song, J Hu, C Ma, H Liu, Z Li… - International Journal of …, 2024 - Taylor & Francis
The development of numerous diseases is significantly influenced by inflammation.
Macrophage-derived exosomes (M-Exos) play a role in controlling inflammatory reactions in …

Apigenin alleviates diabetic endothelial dysfunction through activating AMPK/PI3K/Akt/eNOS and Nrf2/HO‐1 signaling pathways

L Miao, MS Cheong, C Zhou, M Farag… - Food …, 2023 - Wiley Online Library
Abstract Apigenin (4′, 5, 7‐trihydroxyflavone) is a natural flavone reported to present anti‐
diabetic and anti‐oxidative bioactivities. The effect of apigenin to mitigate endothelial …

Deciphering the shared mechanisms of Gegen Qinlian Decoction in treating type 2 diabetes and ulcerative colitis via bioinformatics and machine learning

F Hu, L Xiong, Z Li, L Li, L Wang, X Wang… - Frontiers in …, 2024 - frontiersin.org
Background Although previous clinical studies and animal experiments have demonstrated
the efficacy of Gegen Qinlian Decoction (GQD) in treating Type 2 Diabetes Mellitus (T2DM) …