Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis
Intense genome sequencing of Pseudomonas aeruginosa isolates from cystic fibrosis (CF)
airways has shown inefficient eradication of the infecting bacteria, as well as previously …
airways has shown inefficient eradication of the infecting bacteria, as well as previously …
The Pseudomonas aeruginosa Pan-Genome Provides New Insights on Its Population Structure, Horizontal Gene Transfer, and Pathogenicity
The huge increase in the availability of bacterial genomes led us to a point in which we can
investigate and query pan-genomes, for example, the full set of genes of a given bacterial …
investigate and query pan-genomes, for example, the full set of genes of a given bacterial …
Genomics of antibiotic‐resistance prediction in Pseudomonas aeruginosa
Antibiotic resistance is a worldwide health issue spreading quickly among human and
animal pathogens, as well as environmental bacteria. Misuse of antibiotics has an impact on …
animal pathogens, as well as environmental bacteria. Misuse of antibiotics has an impact on …
Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium
The International Pseudomonas aeruginosa Consortium is sequencing over 1000 genomes
and building an analysis pipeline for the study of Pseudomonas genome evolution, antibiotic …
and building an analysis pipeline for the study of Pseudomonas genome evolution, antibiotic …
Seeking the source of Pseudomonas aeruginosa infections in a recently opened hospital: an observational study using whole-genome sequencing
Objectives Pseudomonas aeruginosa is a common nosocomial pathogen responsible for
significant morbidity and mortality internationally. Patients may become colonised or infected …
significant morbidity and mortality internationally. Patients may become colonised or infected …
Comparative genomics of clinical strains of Pseudomonas aeruginosa strains isolated from different geographic sites
The large and complex genome of Pseudomonas aeruginosa, which consists of significant
portions (up to 20%) of transferable genetic elements contributes to the rapid development …
portions (up to 20%) of transferable genetic elements contributes to the rapid development …
Genetic Diversity, Distribution, and Genomic Characterization of Antibiotic Resistance and Virulence of Clinical Pseudomonas aeruginosa Strains in Kenya
S Kiyaga, C Kyany'a, AW Muraya, HJ Smith… - Frontiers in …, 2022 - frontiersin.org
Pseudomonas aeruginosa is a leading cause of nosocomial infections worldwide. It can
produce a range of debilitating infections, have a propensity for developing antimicrobial …
produce a range of debilitating infections, have a propensity for developing antimicrobial …
Genomic characterisation of an international Pseudomonas aeruginosa reference panel indicates that the two major groups draw upon distinct mobile gene pools
Pseudomonas aeruginosa is an important opportunistic pathogen, especially in the context
of infections of cystic fibrosis (CF). In order to facilitate coordinated study of this pathogen, an …
of infections of cystic fibrosis (CF). In order to facilitate coordinated study of this pathogen, an …
Pseudomonas aeruginosa adaptation and diversification in the non-cystic fibrosis bronchiectasis lung
To characterise Pseudomonas aeruginosa populations during chronic lung infections of non-
cystic fibrosis bronchiectasis patients, we used whole-genome sequencing to 1) assess the …
cystic fibrosis bronchiectasis patients, we used whole-genome sequencing to 1) assess the …
Common adaptive strategies underlie within-host evolution of bacterial pathogens
YE Gatt, H Margalit - Molecular biology and evolution, 2021 - academic.oup.com
Within-host adaptation is a hallmark of chronic bacterial infections, involving substantial
genomic changes. Recent large-scale genomic data from prolonged infections allow the …
genomic changes. Recent large-scale genomic data from prolonged infections allow the …