[HTML][HTML] Overview of hepatitis C infection, molecular biology, and new treatment

AA Rabaan, SH Al-Ahmed, AM Bazzi… - Journal of infection and …, 2020 - Elsevier
Abstract The World Health Organization estimates that 71 million people worldwide have
chronic hepatitis C viral infection. A major challenge is overall lack of public awareness of …

EASL recommendations on treatment of hepatitis C: final update of the series☆

JM Pawlotsky, F Negro, A Aghemo, M Berenguer… - Journal of …, 2020 - Elsevier
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with
approximately 71 million chronically infected individuals worldwide. Clinical care for patients …

Direct-acting antiviral agents for hepatitis C virus infection—From drug discovery to successful implementation in clinical practice

C Dietz, B Maasoumy - Viruses, 2022 - mdpi.com
Today, hepatitis C virus infection affects up to 1.5 million people per year and is responsible
for 29 thousand deaths per year. In the 1970s, the clinical observation of unclear, transfusion …

EASL recommendations on treatment of hepatitis C 2018

JM Pawlotsky, F Negro, A Aghemo, M Berenguer… - Journal of …, 2018 - Elsevier
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with
approximately 71 million chronically infected individuals worldwide. Clinical care for patients …

An update on direct antiviral agents for the treatment of hepatitis C

C Stanciu, CM Muzica, I Girleanu… - Expert opinion on …, 2021 - Taylor & Francis
Introduction: The development of direct-acting antiviral (DAA) agents for the treatment of
hepatitis C virus (HCV) infection has completely transformed the management of this …

Predictors of hepatocellular carcinoma occurrence after direct‐acting antiviral therapy in patients with hepatitis C virus infection

T Watanabe, Y Tokumoto, K Joko… - Hepatology …, 2019 - Wiley Online Library
Aim The predictors for the development of hepatocellular carcinoma (HCC) after direct‐
acting antiviral (DAA) treatment were investigated. Methods A total of 1174 patients with …

Re-treatment of hepatitis C infection after multiple failures of direct-acting antiviral therapy

DS Fierer, DL Wyles - Open Forum Infectious Diseases, 2020 - academic.oup.com
Background Direct-acting antiviral (DAA) therapies for hepatitis C virus (HCV) result in initial
cure rates of 95% to 99% and re-treatment cure rates of 95%. Nevertheless, given the sheer …

Efficacy and safety of elbasvir/grazoprevir in participants with hepatitis C virus genotype 1, 4, or 6 infection from the Asia–Pacific region and Russia: final results from …

L Wei, JD Jia, FS Wang, JQ Niu… - Journal of …, 2019 - Wiley Online Library
Abstract Background and Aim Although treatment with direct‐acting antivirals has
dramatically improved morbidity and mortality attributable to chronic hepatitis C virus …

Full-genome next-generation sequencing of hepatitis C virus to assess the accuracy of genotyping by the commercial assay LiPA and the prevalence of resistance …

KT Christensen, F Pierard, K Beuselinck… - Journal of Clinical …, 2022 - Elsevier
Background Although most currently used regimens for Hepatitis C virus (HCV) infections
can be initiated without prior knowledge of genotype and subtype, genotyping is still useful …

Simple new clinical score to predict hepatocellular carcinoma after sustained viral response with direct-acting antivirals

T Watanabe, Y Tokumoto, K Joko, K Michitaka… - Scientific Reports, 2023 - nature.com
The time point of the most precise predictor of hepatocellular carcinoma (HCC) development
after viral eradication with direct-acting antiviral (DAA) therapy is unclear. In this study we …