[HTML][HTML] Diabetic macular edema: current understanding, molecular mechanisms and therapeutic implications
J Zhang, J Zhang, C Zhang, J Zhang, L Gu, D Luo… - Cells, 2022 - mdpi.com
Diabetic retinopathy (DR), with increasing incidence, is the major cause of vision loss and
blindness worldwide in working-age adults. Diabetic macular edema (DME) remains the …
blindness worldwide in working-age adults. Diabetic macular edema (DME) remains the …
Macrophage plasticity, polarization, and function in health and disease
A Shapouri‐Moghaddam… - Journal of cellular …, 2018 - Wiley Online Library
Macrophages are heterogeneous and their phenotype and functions are regulated by the
surrounding micro‐environment. Macrophages commonly exist in two distinct subsets: 1) …
surrounding micro‐environment. Macrophages commonly exist in two distinct subsets: 1) …
Human chimeric antigen receptor macrophages for cancer immunotherapy
M Klichinsky, M Ruella, O Shestova, XM Lu… - Nature …, 2020 - nature.com
Chimeric antigen receptor (CAR) T cell therapy has shown promise in hematologic
malignancies, but its application to solid tumors has been challenging,,–. Given the unique …
malignancies, but its application to solid tumors has been challenging,,–. Given the unique …
[HTML][HTML] Multi-sensory gamma stimulation ameliorates Alzheimer's-associated pathology and improves cognition
AJ Martorell, AL Paulson, HJ Suk, F Abdurrob… - Cell, 2019 - cell.com
We previously reported that inducing gamma oscillations with a non-invasive light flicker
(gamma entrainment using sensory stimulus or GENUS) impacted pathology in the visual …
(gamma entrainment using sensory stimulus or GENUS) impacted pathology in the visual …
Microglia in depression: current perspectives
Major depressive disorder (MDD) is a prevalent psychiatric disease that involves
malfunctions of different cell types in the brain. Accumulating studies started to reveal that …
malfunctions of different cell types in the brain. Accumulating studies started to reveal that …
[HTML][HTML] Neuroimmunology of traumatic brain injury: time for a paradigm shift
YN Jassam, S Izzy, M Whalen, DB McGavern… - Neuron, 2017 - cell.com
Traumatic brain injury (TBI) is a leading cause of morbidity and disability, with a
considerable socioeconomic burden. Heterogeneity of pathoanatomical subtypes and …
considerable socioeconomic burden. Heterogeneity of pathoanatomical subtypes and …
The mechanisms of NLRP3 inflammasome/pyroptosis activation and their role in Parkinson's disease
S Wang, YH Yuan, NH Chen, HB Wang - International …, 2019 - Elsevier
Parkinson's disease (PD) is a typical neurodegenerative disease and the pathological
feature of which is the death of dopamine neurons in the substantia nigra region. At present …
feature of which is the death of dopamine neurons in the substantia nigra region. At present …
Neuroinflammation in the central nervous system: Symphony of glial cells
Q Yang, J Zhou - Glia, 2019 - Wiley Online Library
Neuroinflammation in the central nervous system (CNS) is an important subject of
neuroimmunological research. Emerging evidence suggests that neuroinflammation is a key …
neuroimmunological research. Emerging evidence suggests that neuroinflammation is a key …
Inflammation and post‐traumatic stress disorder
H Hori, Y Kim - Psychiatry and clinical neurosciences, 2019 - Wiley Online Library
While post‐traumatic stress disorder (PTSD) is currently diagnosed based solely on classic
psychological and behavioral symptoms, a growing body of evidence has highlighted a link …
psychological and behavioral symptoms, a growing body of evidence has highlighted a link …
Microbiome–microglia connections via the gut–brain axis
R Abdel-Haq, JCM Schlachetzki, CK Glass… - Journal of Experimental …, 2019 - rupress.org
Microglia, the resident immune cells in the brain, are essential for modulating neurogenesis,
influencing synaptic remodeling, and regulating neuroinflammation by surveying the brain …
influencing synaptic remodeling, and regulating neuroinflammation by surveying the brain …